Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.71 |
| ▸ | HPGD | P15428 | 2/20 | 0.71 |
| ▸ | LMNA | P02545 | 2/20 | 0.71 |
| ▸ | GAA | P10253 | 1/20 | 0.71 |
| ▸ | TSHR | P16473 | 4/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.70 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.68 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.64 |
| ▸ | CACNA1F | O60840 | 3/20 | 0.60 |
| ▸ | CACNA1D | Q01668 | 3/20 | 0.60 |
| ▸ | CACNA1S | Q13698 | 3/20 | 0.60 |
| ▸ | CACNA1C | Q13936 | 3/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7817206 | 0.88 | KDM4E (0.88) | ADORA3ALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL3330194 | 0.88 | ADORA3 (0.76) | ADORA3ALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL20610477 | 0.87 | ADORA3 (1.00) | ADORA3ALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL7158354 | 0.86 | ADORA3 (0.78) | ADORA3ALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL14576820 | 0.85 | ADORA3 (0.68) | ADORA3ALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL11835842 | 0.85 | ADORA3 (0.72) | ADORA3ALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL8288455 | 0.84 | ADORA3 (0.74) | ADORA3ALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL7163210 | 0.84 | ADORA3 (0.70) | ADORA3ALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL3032293 | 0.84 | KDM4E (0.80) | ADORA3ALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL7159073 | 0.83 | ADORA3 (1.00) | ADORA3ALDH1A1KDM4EHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0458823-B1 | A PROCESS FOR PREPARATION OF ENANTIOMERICALLY PURE POLYSUBSTITUTED 1,4-DIHYDROPYRIDINES | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1993-10-13 | — | — | EP | disclosed |
| US-5245039-A | PROCESS FOR PREPARATION OF ENANTIOMERICALLY PURE POLYSUBSTITUTED 1,4-DIHYDROPYRIDINES | BOEHRINGER MANNHEIM ITALIA (IT) | 1993-09-14 | — | — | US | disclosed |
| EP-0458823-A1 | A PROCESS FOR PREPARATION OF ENANTIOMERICALLY PURE POLYSUBSTITUTED 1,4-DIHYDROPYRIDINES. | BOEHRINGER MANNHEIM ITALIA (IT) | 1991-12-04 | — | — | EP | disclosed |
| WO-1990009376-A1 | A PROCESS FOR PREPARATION OF ENANTIOMERICALLY PURE POLYSUBSTITUTED 1,4-DIHYDROPYRIDINES | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1990-08-23 | — | — | WO | disclosed |
| EP-0383320-A1 | A process for preparation of enantiomerically pure polysubstituted 1,4-dihydropyridines | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1990-08-22 | — | — | EP | disclosed |