Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | CNR1 | P21554 | 3/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9784864 | 0.99 | BCHE (0.47) | BCHETP53ALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL9331538 | 0.94 | BCHE (0.46) | BCHETP53ALDH1A1L3MBTL1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9332148 | 0.93 | LMNA (0.45) | BCHETP53ALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL9331559 | 0.90 | LMNA (0.57) | TP53ALDH1A1SMN1; SMN2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9331386 | 0.89 | LMNA (0.56) | TP53ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9504338 | 0.89 | LMNA (0.56) | BCHETP53SMN1; SMN2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9759697 | 0.88 | BCHE (0.42) | BCHETP53ALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL9504379 | 0.88 | LMNA (0.45) | TP53ALDH1A1L3MBTL1SMN1; SMN2MEN1 | |
| Hydrochloric Acid SCHEMBL9784944 | 0.87 | LMNA (0.44) | TP53ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8973051 | 0.87 | NAMPT (0.43) | BCHETP53L3MBTL1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0346238-B1 | ANALGESIC PHENOTHIAZINE DERIVATIVES | RHONE-POULENC SANTE (FR) | 1993-06-09 | — | — | EP | claimed |
| US-5049669-A | Also diuretics | RHONE-POULENC SANTE (FR) | 1991-09-17 | — | — | US | disclosed |