Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 11/20 | 0.40 |
| ▸ | KDM1A | O60341 | 7/20 | 0.40 |
| ▸ | MAOA | P21397 | 7/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL5499312 | 0.98 | MAOB (0.41) | MAOBKDM1AMAOAHTR2CHTR2A | |
| SCHEMBL9716878 | 0.77 | HTR2C (0.36) | MAOBKDM1AMAOAHTR2CHTR2A | |
| SCHEMBL29662225 | 0.76 | KDM1A (0.52) | MAOBKDM1AMAOA | |
| SCHEMBL10363387 | 0.75 | HTR2C (0.35) | MAOBKDM1AMAOAHTR2CHTR2A | |
| SCHEMBL30388895 | 0.75 | HTR2C (0.35) | MAOBKDM1AMAOAHTR2CHTR2A | |
| SCHEMBL19019983 | 0.73 | HTR2C (0.34) | MAOBKDM1AMAOAHTR2C | |
| SCHEMBL11295093 | 0.72 | KDM1A (0.46) | MAOBKDM1AHTR2ASIGMAR1 | |
| SCHEMBL21845155 | 0.72 | KDM1A (0.46) | MAOBKDM1AHTR2ASIGMAR1 | |
| SCHEMBL17963525 | 0.72 | KDM1A (0.55) | MAOBKDM1AMAOA | |
| SCHEMBL28259691 | 0.72 | HTR2C (0.33) | MAOBKDM1AMAOAHTR2CHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0335375-B1 | ANTIHYPERLIPIDEMIC AND ANTIATHEROSCLEROTIC COMPOUNDS AND COMPOSITIONS | WARNER-LAMBERT COMPANY (US) | 1993-06-09 | — | — | EP | disclosed |
| US-5030653-A | N-2,6-dialkyl- or n-2,6-dialkoxyphenyl-n-arylalkylurea compounds | WARNER-LAMBERT COMPANY (US) | 1991-07-09 | — | — | US | disclosed |
| US-4999373-A | Phenyl ureas or thioureas substituted with a xanthene or thioxanthene group | WARNER-LAMBERT COMPANY (US) | 1991-03-12 | — | — | US | disclosed |
| US-4948806-A | N-2,6-DIALKYL-OR N-2,6-DIALKOXYPHENYL-N'-ARYLALKYLUREA | WARNER-LAMBERT COMPANY (US) | 1990-08-14 | — | — | US | disclosed |
| EP-0335375-A2 | Antihyperlipidemic and antiatherosclerotic compounds and compositions | WARNER-LAMBERT COMPANY (US) | 1989-10-04 | — | — | EP | disclosed |
| US-4868210-A | PHENYL UREAS AND PHENYL THIOUREAS | WARNER-LAMBERT COMPANY (US) | 1989-09-19 | — | — | US | disclosed |