SCHEMBL9716878

SCHEMBL9716878

CC1CC(C)(C)c2ccccc2C1(C)C

nearest known ligand 0.42

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 1/20 0.36
RARG P13631 1/20 0.35
KDM1A O60341 4/20 0.33
MAOA P21397 4/20 0.33
MAOB P27338 4/20 0.33
NOTUM Q6P988 2/20 0.32
HTR2A P28223 1/20 0.31
CNR2 P34972 1/20 0.31
SIGMAR1 Q99720 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10363387 0.98 HTR2C (0.35) HTR2CRARGKDM1AMAOAMAOB
SCHEMBL9501829 0.77 MAOB (0.40) HTR2CKDM1AMAOAMAOBHTR2A
SCHEMBL30388895 0.77 HTR2C (0.35) HTR2CKDM1AMAOAMAOBNOTUM
SCHEMBL10686968 0.76 RARG (0.40) RARG
SCHEMBL4874095 0.76 RARG (0.40) RARG
SCHEMBL9211974 0.76 RARG (0.40) RARG
SCHEMBL10684467 0.76 RARG (0.40) RARG
SCHEMBL19019983 0.75 HTR2C (0.34) HTR2CKDM1AMAOAMAOBNOTUM
Benzene SCHEMBL5499312 0.75 MAOB (0.41) HTR2CKDM1AMAOAMAOBHTR2A
SCHEMBL24806899 0.75 KDM1A (0.37) HTR2CRARGKDM1AHTR2ASIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0301375-B1 BICYCLIC ALDEHYDES L. GIVAUDAN & CIE Société Anonyme (CH) 1992-03-18 EP disclosed
EP-0301375-A2 Bicyclic aldehydes L. GIVAUDAN & CIE Société Anonyme (CH) 1989-02-01 EP disclosed
US-4634548-A PERFUMES, FLAVORS GIVAUDAN CORPORATION (US) 1987-01-06 US disclosed
EP-0115274-B1 EPOXIDES OF BICYCLIC COMPOUNDS, PROCESS FOR THEIR PREPARATION AND PERFUMED AND/OR FLAVOURED COMPOSITIONS CONTAINING THEM L. GIVAUDAN & CIE Société Anonyme (CH) 1986-11-05 EP disclosed
EP-0115274-A1 Epoxides of bicyclic compounds, process for their preparation and perfumed and/or flavoured compositions containing them L. GIVAUDAN & CIE Société Anonyme (CH) 1984-08-08 EP disclosed