Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRB3 | P28472 | 18/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 15/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 15/20 | 0.35 |
| ▸ | GABRP | O00591 | 10/20 | 0.35 |
| ▸ | GABRD | O14764 | 10/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 10/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 10/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 10/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 10/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 10/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 10/20 | 0.35 |
| ▸ | GABRE | P78334 | 10/20 | 0.35 |
| ▸ | GABRA6 | Q16445 | 10/20 | 0.35 |
| ▸ | GABRG1 | Q8N1C3 | 10/20 | 0.35 |
| ▸ | GABRG3 | Q99928 | 10/20 | 0.35 |
| ▸ | GABRQ | Q9UN88 | 10/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9208952 | 1.00 | GABRB3 (0.35) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL9218561 | 0.84 | GAA (0.39) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL9501896 | 0.84 | GAA (0.39) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL9501595 | 0.82 | GABRB3 (0.34) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL9215567 | 0.82 | GABRB3 (0.34) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL9502907 | 0.80 | GABRB3 (0.39) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL9211530 | 0.80 | GABRB3 (0.39) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL9215522 | 0.78 | GABRB3 (0.38) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL9502899 | 0.78 | GABRB3 (0.38) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL9500624 | 0.77 | GAA (0.40) | GABRB3GABRA2GABRB2GABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5189053-A | Insecticide, acaricide and endoparasiticide | SCHERING AGROCHEMICALS LIMITED (GB) | 1993-02-23 | — | — | US | disclosed |
| US-5109012-A | 2-IMIDAZOL(IN)E SUBSTITUTED ARYL-1,2,3-TRIAZOLE PESTICIDES | SCHERING AGROCHEMICALS LIMITED (GB) | 1992-04-28 | — | — | US | disclosed |