Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 6/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.46 |
| ▸ | HTR2A | P28223 | 4/20 | 0.44 |
| ▸ | HRH1 | P35367 | 3/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.43 |
| ▸ | ICMT | O60725 | 1/20 | 0.40 |
| ▸ | ALB | P02768 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27611422 | 0.98 | KCNH2 (0.49) | KCNH2SIGMAR1HTR2AHRH1OPRM1 | |
| SCHEMBL10513477 | 0.86 | HTR2A (0.47) | KCNH2SIGMAR1HTR2AHRH1OPRM1 | |
| SCHEMBL14288496 | 0.84 | SIGMAR1 (0.44) | KCNH2SIGMAR1HTR2AHRH1OPRM1 | |
| Hydrochloric Acid SCHEMBL27522779 | 0.82 | KCNH2 (0.43) | KCNH2SIGMAR1HTR2AOPRM1OPRD1 | |
| SCHEMBL28513356 | 0.81 | KCNH2 (0.48) | KCNH2SIGMAR1HTR2AHRH1ICMT | |
| SCHEMBL28024024 | 0.81 | KCNH2 (0.48) | KCNH2SIGMAR1HTR2AHRH1ICMT | |
| Water SCHEMBL28973048 | 0.81 | KCNH2 (0.46) | KCNH2SIGMAR1HTR2AHRH1OPRM1 | |
| SCHEMBL27819823 | 0.81 | KCNH2 (0.50) | KCNH2SIGMAR1HTR2AOPRM1OPRD1 | |
| SCHEMBL11451801 | 0.80 | KCNH2 (0.50) | KCNH2SIGMAR1HTR2AHRH1OPRM1 | |
| Hydrochloric Acid SCHEMBL28780915 | 0.80 | KCNH2 (0.47) | KCNH2SIGMAR1HTR2AHRH1ICMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0200404-B1 | SOLID PHASE PROCESS FOR SYNTHESIZING PEPTIDES | ALPHA-1 BIOMEDICALS, INC. (US) | 1993-06-30 | — | — | EP | disclosed |
| US-4855407-A | Solid phase process for synthesizing peptides | ALPHA-1 BIOMEDICALS, INC. (US) | 1989-08-08 | — | — | US | disclosed |
| EP-0200404-A2 | Solid phase process for synthesizing peptides | ALPHA-1 BIOMEDICALS, INC. (US) | 1986-11-05 | — | — | EP | disclosed |