SCHEMBL9502109

SCHEMBL9502109

O=C(c1ccc(Oc2ccccc2)cc1)c1ccc2cc(C(=O)c3ccc(Oc4ccccc4)cc3)ccc2c1

nearest known ligand 0.72

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SRD5A2 P31213 6/20 0.72
MEN1 O00255 1/20 0.62
NPC1 O15118 1/20 0.62
RAB9A P51151 1/20 0.62
KMT2A Q03164 1/20 0.62
POLB P06746 1/20 0.60
PARP10 Q53GL7 1/20 0.58
ATM Q13315 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
ELANE P08246 1/20 0.52
AKR1C3 P42330 1/20 0.52
BCL2 P10415 1/20 0.51
MCL1 Q07820 1/20 0.51
BAD Q92934 1/20 0.51
ERCC5 P28715 1/20 0.50
FEN1 P39748 1/20 0.50
ACHE P22303 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13465507 0.96 SRD5A2 (0.68) SRD5A2MEN1NPC1RAB9AKMT2A
SCHEMBL8461109 0.95 SRD5A2 (0.77) SRD5A2MEN1NPC1RAB9AKMT2A
SCHEMBL2866068 0.90 SRD5A2 (0.88) SRD5A2POLBPARP10ELANEAKR1C3
SCHEMBL13599782 0.90 SRD5A2 (0.88) SRD5A2POLBPARP10ELANEAKR1C3
SCHEMBL1082112 0.90 SRD5A2 (0.88) SRD5A2POLBPARP10ELANEAKR1C3
SCHEMBL9536469 0.90 SRD5A2 (0.88) SRD5A2POLBPARP10ELANEAKR1C3
SCHEMBL235530 0.90 SRD5A2 (0.88) SRD5A2POLBPARP10ELANEAKR1C3
SCHEMBL1081660 0.89 SRD5A2 (0.72) SRD5A2POLBPARP10ATMTDP1
SCHEMBL10593556 0.89 SRD5A2 (0.72) SRD5A2POLBPARP10ATMTDP1
SCHEMBL26624065 0.89 SRD5A2 (0.72) SRD5A2POLBPARP10ATMTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0540653-A1 PROCESS FOR PREPARING DIKETONES AND KETO-ACIDS EASTMAN KODAK COMPANY (US) 1993-05-12 EP disclosed
WO-1992007894-A1 ETHER-KETONE-SULPHONE COPOLYMERS RAYCHEM LIMITED (GB) 1992-05-14 WO disclosed
US-5107029-A PROCESS FOR PREPARING DIKETONES AND KETO-ACIDS EASTMAN KODAK COMPANY (US) 1992-04-21 US disclosed
WO-1992001662-A1 PROCESS FOR PREPARING DIKETONES AND KETO-ACIDS EASTMAN KODAK COMPANY (US) 1992-02-06 WO disclosed
EP-0423220-A1 ETHERSULPHONE POLYMERS RAYCHEM LIMITED (GB) 1991-04-24 EP disclosed
US-4990589-A Engineering thermoplastic resin RAYCHEM LIMITED (GB) 1991-02-05 US disclosed
EP-0407386-A1 PREPARATION OF POLY(ARYLENE ETHER KETONES) RAYCHEM LIMITED (GB) 1991-01-16 EP disclosed
WO-1990000573-A1 ETHERSULPHONE POLYMERS RAYCHEM LIMITED (GB) 1990-01-25 WO disclosed
WO-1989004848-A1 PREPARATION OF POLY(ARYLENE ETHER KETONES) RAYCHEM LIMITED (GB) 1989-06-01 WO disclosed
EP-0315441-A2 Poly(arylene ether ketones) RAYCHEM LIMITED (GB) 1989-05-10 EP disclosed