Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 20/20 | 0.67 |
| ▸ | DHFR | P00374 | 1/20 | 0.46 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9502259 | 0.88 | DHODH (0.55) | DHODH | |
| SCHEMBL8794498 | 0.88 | DHODH (0.67) | DHODHDHFRALKBH5 | |
| SCHEMBL8732564 | 0.86 | DHODH (0.68) | DHODHDHFRALKBH5 | |
| SCHEMBL17594047 | 0.84 | DHODH (0.64) | DHODHDHFRALKBH5 | |
| SCHEMBL8794638 | 0.83 | DHODH (0.57) | DHODHDHFRALKBH5 | |
| SCHEMBL8793708 | 0.83 | DHODH (0.57) | DHODHDHFRALKBH5 | |
| SCHEMBL18075841 | 0.83 | DHODH (0.51) | DHODH | |
| SCHEMBL8793853 | 0.82 | DHODH (0.60) | DHODH | |
| SCHEMBL5497084 | 0.81 | DHODH (0.60) | DHODH | |
| SCHEMBL9502210 | 0.81 | DHODH (1.00) | DHODHDHFRALKBH5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0305952-B1 | SUBSTITUTED 2-PHENYL-4-QUINOLINE-CARBOXYLIC ACIDS | AMERICAN CYANAMID COMPANY (US) | 1993-06-02 | — | — | EP | claimed |