Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | CFTR | P13569 | 1/20 | 0.46 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.45 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | TYMS | P04818 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL9529275 | 0.93 | SMN1; SMN2 (0.47) | SMN1; SMN2CFTRGOPCMAPTLMNA | |
| SCHEMBL21325292 | 0.83 | NPSR1 (0.49) | SMN1; SMN2CFTRGOPCMAPTLMNA | |
| SCHEMBL29502553 | 0.83 | NPSR1 (0.49) | SMN1; SMN2CFTRGOPCMAPTLMNA | |
| SCHEMBL6271326 | 0.83 | NPSR1 (0.49) | SMN1; SMN2CFTRGOPCMAPTLMNA | |
| SCHEMBL4028258 | 0.82 | NPSR1 (0.49) | SMN1; SMN2CFTRGOPCMAPTLMNA | |
| SCHEMBL9975204 | 0.81 | CFTR (0.46) | SMN1; SMN2CFTRGOPCMAPTLMNA | |
| SCHEMBL11848675 | 0.79 | CFTR (0.47) | SMN1; SMN2CFTRGOPCMAPTLMNA | |
| SCHEMBL9529272 | 0.78 | TDP2 (0.47) | SMN1; SMN2MAPTLMNAMEN1KMT2A | |
| SCHEMBL4591907 | 0.77 | CFTR (0.46) | SMN1; SMN2CFTRGOPCMAPTLMNA | |
| SCHEMBL21605709 | 0.77 | ATM (0.41) | SMN1; SMN2CFTRGOPCMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0306096-B1 | PROCESS FOR PREPARING DIPHENYL ETHERS | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1993-06-09 | — | — | EP | disclosed |
| US-4927945-A | Process for preparing diphenyl ethers | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ, B.V. (NL) | 1990-05-22 | — | — | US | disclosed |
| EP-0306096-A1 | Process for preparing diphenyl ethers | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1989-03-08 | — | — | EP | disclosed |