Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 7/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | CES1 | P23141 | 5/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30605720 | 0.86 | TDP1 (0.46) | FAAHPKML3MBTL1TDP1KDM4E | |
| SCHEMBL7675284 | 0.85 | TDP1 (0.47) | FAAHPKML3MBTL1TDP1KDM4E | |
| SCHEMBL4500023 | 0.83 | L3MBTL1 (0.60) | FAAHPKML3MBTL1TDP1KDM4E | |
| SCHEMBL1722473 | 0.83 | SMN1; SMN2 (0.57) | L3MBTL1TDP1KDM4EALDH1A1TSHR | |
| SCHEMBL17714455 | 0.80 | TDP1 (0.50) | PKML3MBTL1TDP1KDM4EALDH1A1 | |
| SCHEMBL21957938 | 0.80 | TDP1 (0.50) | PKML3MBTL1TDP1KDM4EALDH1A1 | |
| SCHEMBL2130083 | 0.80 | SMN1; SMN2 (0.57) | L3MBTL1TDP1KDM4EKMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL21957930 | 0.79 | TDP1 (0.49) | PKML3MBTL1TDP1KDM4EALDH1A1 | |
| SCHEMBL2732104 | 0.79 | TDP1 (0.49) | PKML3MBTL1TDP1KDM4EALDH1A1 | |
| SCHEMBL27497541 | 0.79 | TDP1 (0.49) | PKML3MBTL1TDP1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0548291-A1 | PYRIDYLTHIO OR PYRIDYLOXY ALKANOIC ACIDS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-06-30 | — | — | EP | disclosed |
| WO-1992005156-A1 | PYRIDYLTHIO OR PYRIDYLOXY ALKANOIC ACIDS | SMITHKLINE BEECHAM CORPORATION (US) | 1992-04-02 | — | — | WO | disclosed |