Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.39 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.39 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.39 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9502975 | 1.00 | SMN1; SMN2 (0.46) | SMN1; SMN2CYP3A4CYP2C19POLBTHRB | |
| SCHEMBL6377119 | 0.84 | EPHX2 (0.48) | SMN1; SMN2KMT2ATBXA2RTBXAS1MEN1 | |
| SCHEMBL9216119 | 0.84 | SMN1; SMN2 (0.45) | SMN1; SMN2CYP3A4CYP2C19POLBKMT2A | |
| SCHEMBL9214494 | 0.84 | EPHX2 (0.48) | SMN1; SMN2KMT2ATBXA2RTBXAS1MEN1 | |
| SCHEMBL9216081 | 0.84 | SMN1; SMN2 (0.45) | SMN1; SMN2CYP3A4CYP2C19POLBKMT2A | |
| SCHEMBL9215256 | 0.82 | EPHX2 (0.50) | SMN1; SMN2CYP2C19TBXA2RTBXAS1PLOD2 | |
| SCHEMBL9211842 | 0.82 | EPHX2 (0.52) | SMN1; SMN2KMT2ATBXA2RTBXAS1MEN1 | |
| SCHEMBL9211848 | 0.82 | EPHX2 (0.52) | SMN1; SMN2KMT2ATBXA2RTBXAS1MEN1 | |
| SCHEMBL9217826 | 0.82 | EPHX2 (0.50) | SMN1; SMN2CYP2C19TBXA2RTBXAS1PLOD2 | |
| SCHEMBL9211746 | 0.81 | SMN1; SMN2 (0.54) | SMN1; SMN2CYP3A4CYP2C19POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5140109-A | — | — | None | — | — | JP | disclosed |
| JP-H05140109-A | PRODUCTION OF N-CYANO-N'-(2-NITROXYETHYL)-3-PYRIDINECARBOXYIMIDAMIDE | KIRIN BREWERY CO LTD | 1993-06-08 | — | — | JP | disclosed |