Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 5/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | TBXAS1 | P24557 | 4/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9217826 | 1.00 | EPHX2 (0.50) | EPHX2CYP2C9CYP2C19TBXAS1TBXA2R | |
| SCHEMBL9211715 | 0.88 | EPHX2 (0.46) | EPHX2CYP2C9CYP2C19TBXAS1TBXA2R | |
| SCHEMBL9211713 | 0.88 | EPHX2 (0.46) | EPHX2CYP2C9CYP2C19TBXAS1TBXA2R | |
| Hydrochloric Acid SCHEMBL9218717 | 0.86 | EPHX2 (0.45) | EPHX2CYP2C9CYP2C19TBXAS1TBXA2R | |
| Hydrochloric Acid SCHEMBL9218712 | 0.86 | EPHX2 (0.45) | EPHX2CYP2C9CYP2C19TBXAS1TBXA2R | |
| SCHEMBL9214494 | 0.82 | EPHX2 (0.48) | EPHX2TBXAS1TBXA2RLMNASMN1; SMN2 | |
| SCHEMBL6377119 | 0.82 | EPHX2 (0.48) | EPHX2TBXAS1TBXA2RLMNASMN1; SMN2 | |
| SCHEMBL9502980 | 0.82 | SMN1; SMN2 (0.46) | CYP2C19TBXAS1TBXA2RLMNASMN1; SMN2 | |
| SCHEMBL9502975 | 0.82 | SMN1; SMN2 (0.46) | CYP2C19TBXAS1TBXA2RLMNASMN1; SMN2 | |
| SCHEMBL9212178 | 0.81 | S1PR3 (0.47) | EPHX2CYP2C9CYP2C19TBXAS1TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0388528-B1 | Carboximidamide derivatives | KIRIN BREWERY (JP) | 1995-09-27 | — | — | EP | claimed |
| EP-0388528-A2 | Carboximidamide derivatives | KIRIN BEER KABUSHIKI KAISHA (JP) | 1990-09-26 | — | — | EP | claimed |
| EP-0388528-B1 | Carboximidamide derivatives | KIRIN BREWERY (JP) | 1995-09-27 | — | — | EP | disclosed |
| US-5272164-A | Carboximidamide derivatives | KIRIN BEER KABUSHIKI KAISHA (JP) | 1993-12-21 | — | — | US | disclosed |
| US-5223508-A | Hypotensive agents, vasodilators | KIRIN BEER KABUSHIKI KAISHA (JP) | 1993-06-29 | — | — | US | disclosed |
| US-5166347-A | Hypotensive agents, cardiovascular disorders, antiischemic agents and anticoagulants | KIRIN BEER KABUSHIKI KAISHA (JP) | 1992-11-24 | — | — | US | disclosed |
| EP-0388528-A2 | Carboximidamide derivatives | KIRIN BEER KABUSHIKI KAISHA (JP) | 1990-09-26 | — | — | EP | disclosed |