Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 9/20 | 0.66 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.49 |
| ▸ | CCKAR | P32238 | 2/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9528505 | 0.93 | CCKBR (0.67) | CCKBROPRD1OPRK1CCKAR | |
| Water SCHEMBL10666524 | 0.92 | CCKBR (0.66) | CCKBROPRD1OPRK1CCKAR | |
| SCHEMBL9501387 | 0.79 | CCKBR (1.00) | CCKBROPRD1OPRK1CCKAR | |
| SCHEMBL9503082 | 0.78 | CCKBR (0.53) | CCKBROPRD1OPRK1CCKAROPRM1 | |
| SCHEMBL10868746 | 0.75 | CCKBR (0.68) | CCKBROPRD1OPRK1OPRM1 | |
| SCHEMBL9499260 | 0.74 | CCKBR (1.00) | CCKBROPRD1OPRK1OPRM1 | |
| Water SCHEMBL9503005 | 0.74 | CCKBR (0.98) | CCKBROPRD1OPRK1OPRM1 | |
| SCHEMBL9501135 | 0.72 | CCKBR (0.64) | CCKBROPRD1OPRK1OPRM1 | |
| SCHEMBL10803682 | 0.70 | CCKBR (0.75) | CCKBROPRD1OPRK1OPRM1 | |
| SCHEMBL9529624 | 0.70 | CCKBR (0.69) | CCKBROPRD1OPRK1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5206238-A | Cholecystokinin antagonists | MERCK & CO., INC. (US) | 1993-04-27 | — | — | US | disclosed |