SCHEMBL9503142

SCHEMBL9503142

CSc1cc(C(=O)O[C@@H]2CC[C@@H]3CCCCC3C2)c(N)c2c1C(=O)c1ccccc1C2=O

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.37
MAPK1 P28482 3/20 0.37
MEN1 O00255 3/20 0.37
KMT2A Q03164 3/20 0.37
THRB P10828 2/20 0.37
GRK6 P43250 1/20 0.37
KDM4E B2RXH2 1/20 0.37
USP2 O75604 1/20 0.37
PKM P14618 1/20 0.37
MCL1 Q07820 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
NPC1 O15118 2/20 0.34
ADORA2A P29274 1/20 0.34
ATM Q13315 1/20 0.33
ALDH1A1 P00352 2/20 0.33
LMNA P02545 2/20 0.33
POLB P06746 1/20 0.33
RECQL P46063 1/20 0.33
RAB9A P51151 1/20 0.32
HTR3E A5X5Y0 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9503133 1.00 MAPT (0.37) MAPTMAPK1MEN1KMT2ATHRB
SCHEMBL9501615 0.92 MAPT (0.37) MAPTMAPK1MEN1KMT2ATHRB
SCHEMBL9501619 0.92 MAPT (0.37) MAPTMAPK1MEN1KMT2ATHRB
SCHEMBL9501634 0.91 MAPT (0.36) MAPTMAPK1MEN1KMT2ATHRB
SCHEMBL9502294 0.91 ALDH1A1 (0.37) MAPTMAPK1MEN1KMT2ATHRB
SCHEMBL9501630 0.91 MAPT (0.36) MAPTMAPK1MEN1KMT2ATHRB
SCHEMBL9502299 0.91 ALDH1A1 (0.37) MAPTMAPK1MEN1KMT2ATHRB
SCHEMBL9502437 0.90 MAPT (0.35) MAPTMAPK1MEN1KMT2ATHRB
SCHEMBL9503220 0.88 SOAT1 (0.34) MAPTMAPK1MEN1KMT2ATHRB
SCHEMBL9503219 0.88 SOAT1 (0.34) MAPTMAPK1MEN1KMT2ATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0307866-B1 DICHROIC COLORING AGENTS FOR LIQUID CRYSTAL DISPLAYS MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-05-12 EP disclosed
US-4883611-A ANTHRAQUINONE COMPOUND CONTAINING DECAHYDRONAPHTHYL GROUP MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1989-11-28 US disclosed
EP-0307866-A2 Dichroic coloring agents for liquid crystal displays MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-03-22 EP disclosed