SCHEMBL9503182

SCHEMBL9503182

NC(=O)C(CC(=O)c1ccccc1)N1CCOCC1

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.79
ALDH1A1 P00352 6/20 0.51
MAPT P10636 4/20 0.51
KMT2A Q03164 3/20 0.51
POLB P06746 2/20 0.51
MAPK1 P28482 2/20 0.51
HSP90AA1 P07900 1/20 0.51
SMN1; SMN2 Q16637 3/20 0.47
TSHR P16473 2/20 0.47
DRD3 P35462 1/20 0.46
CYP2C19 P33261 2/20 0.46
RAB9A P51151 2/20 0.46
NPC1 O15118 1/20 0.46
KDM4E B2RXH2 1/20 0.46
CYP3A4 P08684 1/20 0.46
CYP1A2 P05177 1/20 0.46
CYP2C9 P11712 1/20 0.46
HPGD P15428 1/20 0.46
LMNA P02545 3/20 0.44
HTT P42858 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15599303 0.88 HSD17B10 (1.00) HSD17B10ALDH1A1MAPTKMT2APOLB
SCHEMBL11660119 0.86 HSD17B10 (0.63) HSD17B10ALDH1A1MAPTKMT2APOLB
SCHEMBL9506401 0.83 HSD17B10 (0.55) HSD17B10ALDH1A1MAPTKMT2APOLB
SCHEMBL28902591 0.79 HSD17B10 (0.69) HSD17B10ALDH1A1MAPTKMT2APOLB
SCHEMBL6318911 0.78 CYP2C19 (0.74) HSD17B10ALDH1A1MAPTKMT2APOLB
SCHEMBL6202032 0.76 HSD17B10 (0.64) HSD17B10ALDH1A1MAPTKMT2APOLB
SCHEMBL501353 0.74 HSD17B10 (0.61) HSD17B10ALDH1A1MAPTKMT2APOLB
SCHEMBL27811710 0.73 HSD17B10 (0.73) HSD17B10ALDH1A1MAPTKMT2AMAPK1
Hydrochloric Acid SCHEMBL6048626 0.72 HSD17B10 (0.71) HSD17B10ALDH1A1MAPTKMT2AMAPK1
SCHEMBL2223626 0.71 HSD17B10 (0.58) HSD17B10ALDH1A1MAPTKMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0300325-B1 COMPOSITIONS FOR PROMOTING GROWTH OF ANIMALS COMETEC S.r.l. (IT) 1993-06-16 EP claimed
US-4950669-A SIDE EFFECT REDUCTION COMETEC S.R.L. (IT) 1990-08-21 US claimed
US-4115570-A CENTRAL NERVOUS SYSTEM DEPRESSANTS ISTITUTO CHEMIOTERAPICO ITALIANO, S.P.A. (IT) 1978-09-19 US claimed
JP-1063546-A None JP disclosed
EP-0300325-B1 COMPOSITIONS FOR PROMOTING GROWTH OF ANIMALS COMETEC S.r.l. (IT) 1993-06-16 EP disclosed
US-4950669-A SIDE EFFECT REDUCTION COMETEC S.R.L. (IT) 1990-08-21 US disclosed
EP-0300325-A2 Compositions for promoting growth of animals COMETEC S.r.l. (IT) 1989-01-25 EP disclosed
US-4115570-A CENTRAL NERVOUS SYSTEM DEPRESSANTS ISTITUTO CHEMIOTERAPICO ITALIANO, S.P.A. (IT) 1978-09-19 US disclosed