Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30069469 | 0.87 | HSD17B10 (0.50) | HSD17B10ALDH1A1MAPTKMT2AMMP8 | |
| SCHEMBL4562032 | 0.79 | POLB (0.48) | HSD17B10ALDH1A1KMT2AMMP8POLB | |
| SCHEMBL28902591 | 0.78 | HSD17B10 (0.69) | HSD17B10ALDH1A1MAPTKMT2ATSHR | |
| SCHEMBL15599303 | 0.78 | HSD17B10 (1.00) | HSD17B10ALDH1A1MAPTKMT2ATSHR | |
| SCHEMBL6318911 | 0.77 | CYP2C19 (0.74) | HSD17B10ALDH1A1MAPTKMT2ATSHR | |
| SCHEMBL6985270 | 0.76 | IDO1 (0.50) | HSD17B10ALDH1A1KMT2AMMP8POLB | |
| SCHEMBL9503182 | 0.76 | HSD17B10 (0.79) | HSD17B10ALDH1A1MAPTKMT2ATSHR | |
| SCHEMBL7280926 | 0.75 | LMNA (0.68) | HSD17B10ALDH1A1MAPTKMT2AMMP8 | |
| Hydrochloric Acid SCHEMBL5758790 | 0.75 | DPP4 (0.48) | HSD17B10ALDH1A1KMT2AMMP8POLB | |
| SCHEMBL9516925 | 0.75 | LMNA (0.68) | HSD17B10ALDH1A1MAPTKMT2AMMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1549600-A1 | KETONES | AstraZeneca AB (SE) | 2005-07-06 | — | — | EP | disclosed |
| WO-2004011410-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2004-02-05 | — | — | WO | disclosed |