SCHEMBL9503189

SCHEMBL9503189

N=C(N)N(O)S(=O)(=O)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APOBEC3G Q9HC16 1/20 0.47
HSD11B1 P28845 2/20 0.42
ALDH1A1 P00352 1/20 0.42
KMT2A Q03164 1/20 0.42
CA1 P00915 2/20 0.41
CA2 P00918 2/20 0.41
CA12 O43570 1/20 0.41
CA3 P07451 1/20 0.41
CA4 P22748 1/20 0.41
CA6 P23280 1/20 0.41
CA5A P35218 1/20 0.41
CA7 P43166 1/20 0.41
PLA2G7 Q13093 1/20 0.41
CA9 Q16790 1/20 0.41
CA13 Q8N1Q1 1/20 0.41
CA14 Q9ULX7 1/20 0.41
CA5B Q9Y2D0 1/20 0.41
TSHR P16473 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
HTR6 P50406 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29111496 0.80 APOBEC3G (0.47) APOBEC3GHSD11B1ALDH1A1KMT2ACA1
SCHEMBL28696634 0.74 APOBEC3G (0.54) APOBEC3GHSD11B1ALDH1A1KMT2ACA1
SCHEMBL29202770 0.73 APOBEC3G (0.58) APOBEC3GHSD11B1ALDH1A1KMT2ACA1
SCHEMBL4243059 0.73 APOBEC3G (0.58) APOBEC3GHSD11B1ALDH1A1KMT2ACA1
Acetic Acid SCHEMBL28282465 0.73 KMT2A (0.47) APOBEC3GHSD11B1ALDH1A1KMT2ATSHR
SCHEMBL174173 0.73 HSD11B1 (0.62) HSD11B1ALDH1A1KMT2ACA2SMN1; SMN2
SCHEMBL1925447 0.72 HSD11B1 (0.65) APOBEC3GHSD11B1ALDH1A1KMT2ATSHR
Acetic Acid SCHEMBL27701101 0.72 KMT2A (0.46) APOBEC3GHSD11B1KMT2ATSHRTDP1
SCHEMBL27294672 0.72 SMN1; SMN2 (0.50) ALDH1A1KMT2ACA1CA2CA12
SCHEMBL11034530 0.71 APOBEC3G (0.50) APOBEC3GHSD11B1ALDH1A1KMT2ACA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-5001024-A None JP disclosed
JP-H051024-A SULFONAMIDE DERIVATIVE TOSOH CORP 1993-01-08 JP disclosed