Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CCR2 | P41597 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9503251 | 1.00 | IDH1 (0.39) | IDH1CYP2C19CYP1A2CYP2D6SMN1; SMN2 | |
| SCHEMBL9506587 | 0.89 | SMN1; SMN2 (0.40) | IDH1CYP2C19CYP1A2CYP2D6SMN1; SMN2 | |
| SCHEMBL9506592 | 0.89 | SMN1; SMN2 (0.40) | IDH1CYP2C19CYP1A2CYP2D6SMN1; SMN2 | |
| SCHEMBL9503500 | 0.87 | HPGD (0.40) | SMN1; SMN2MEN1KMT2ANPC1HPGD | |
| SCHEMBL9505297 | 0.86 | HPGD (0.41) | CYP1A2SMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL9504394 | 0.86 | HPGD (0.41) | CYP1A2SMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL9503283 | 0.83 | HPGD (0.42) | SMN1; SMN2MEN1KMT2ANPC1MAPT | |
| SCHEMBL9507128 | 0.82 | MEN1 (0.42) | SMN1; SMN2MEN1KMT2ANPC1HPGD | |
| SCHEMBL9503666 | 0.81 | HPGD (0.43) | SMN1; SMN2MEN1KMT2ANPC1HPGD | |
| SCHEMBL9503407 | 0.76 | SMN1; SMN2 (0.43) | SMN1; SMN2MEN1KMT2ANPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0336561-B1 | 2-PYRIDYLACETIC ACID DERIVATIVES, PREPARATIONS THEREOF, AND COMPOSITIONS CONTAINING THEM | SUNTORY LIMITED (JP) | 1993-07-28 | — | — | EP | claimed |