Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | IDH1 | O75874 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9506592 | 1.00 | SMN1; SMN2 (0.40) | SMN1; SMN2CYP1A2CYP2C19CYP2D6CYP2C9 | |
| SCHEMBL9503245 | 0.89 | IDH1 (0.39) | SMN1; SMN2CYP1A2CYP2C19CYP2D6CYP2C9 | |
| SCHEMBL9503251 | 0.89 | IDH1 (0.39) | SMN1; SMN2CYP1A2CYP2C19CYP2D6CYP2C9 | |
| SCHEMBL9503407 | 0.86 | SMN1; SMN2 (0.43) | SMN1; SMN2TSHRMEN1NPC1RAB9A | |
| SCHEMBL9507126 | 0.85 | SMN1; SMN2 (0.44) | SMN1; SMN2CYP1A2MEN1NPC1GAA | |
| SCHEMBL9505436 | 0.85 | SMN1; SMN2 (0.44) | SMN1; SMN2CYP1A2MEN1NPC1GAA | |
| SCHEMBL9507165 | 0.82 | MEN1 (0.43) | SMN1; SMN2MEN1NPC1RAB9AKMT2A | |
| SCHEMBL9503672 | 0.81 | MEN1 (0.43) | SMN1; SMN2TSHRMEN1NPC1RAB9A | |
| SCHEMBL9503387 | 0.78 | SMN1; SMN2 (0.45) | SMN1; SMN2TSHRMEN1NPC1RAB9A | |
| SCHEMBL9503500 | 0.75 | HPGD (0.40) | SMN1; SMN2MEN1NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0336561-B1 | 2-PYRIDYLACETIC ACID DERIVATIVES, PREPARATIONS THEREOF, AND COMPOSITIONS CONTAINING THEM | SUNTORY LIMITED (JP) | 1993-07-28 | — | — | EP | claimed |