Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | PDE5A | O76074 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11044936 | 0.89 | SCD (0.58) | SCDALDH1A1TDP1NPC1RAB9A | |
| SCHEMBL31540614 | 0.89 | SCD (0.58) | SCDALDH1A1TDP1NPC1RAB9A | |
| SCHEMBL1473123 | 0.85 | SCD (0.55) | SCDALDH1A1TDP1NPC1RAB9A | |
| SCHEMBL11556623 | 0.85 | SCD (0.55) | SCDALDH1A1TDP1NPC1RAB9A | |
| SCHEMBL3800700 | 0.84 | SCD (0.54) | SCDALDH1A1TDP1NPC1RAB9A | |
| SCHEMBL3805044 | 0.83 | SCD (0.53) | SCDALDH1A1TDP1NPC1RAB9A | |
| SCHEMBL7419208 | 0.81 | SMN1; SMN2 (0.45) | SCDALDH1A1TDP1NPC1RAB9A | |
| SCHEMBL83015 | 0.81 | HRH1 (0.54) | SCDALDH1A1TDP1NPC1RAB9A | |
| SCHEMBL11453761 | 0.80 | ALDH1A1 (0.55) | SCDALDH1A1TDP1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL70340 | 0.80 | HRH1 (0.53) | SCDALDH1A1TDP1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0317332-B1 | SULFONANILIDE COMPOUNDS | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1993-05-19 | — | — | EP | disclosed |
| US-4885367-A | ANTIINFLAMMATORY AGENTS, ANTIPYRETICS, ANALGESICS; SIDE EFFECT REDUCTION | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1989-12-05 | — | — | US | disclosed |
| EP-0317332-A2 | Sulfonanilide compounds | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1989-05-24 | — | — | EP | disclosed |