Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.53 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.53 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.53 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | HRH1 | P35367 | 1/20 | 0.53 |
| ▸ | DRD3 | P35462 | 1/20 | 0.53 |
| ▸ | HTR2B | P41595 | 1/20 | 0.53 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 6/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CYP24A1 | Q07973 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9133351 | 0.99 | ADRB2 (0.52) | ADRB2ADRB1HTR1AADRA2ADRD2 | |
| SCHEMBL9501706 | 0.90 | ADRB2 (0.49) | ADRB2ADRB1HTR1AADRA2ADRD2 | |
| SCHEMBL9505720 | 0.90 | ADRB2 (0.49) | ADRB2ADRB1HTR1AADRA2ADRD2 | |
| SCHEMBL9504946 | 0.90 | ADRB2 (0.49) | ADRB2ADRB1HTR1AADRA2ADRD2 | |
| SCHEMBL9505712 | 0.90 | ADRB2 (0.49) | ADRB2ADRB1HTR1AADRA2ADRD2 | |
| SCHEMBL9501699 | 0.90 | ADRB2 (0.49) | ADRB2ADRB1HTR1AADRA2ADRD2 | |
| Hydrochloric Acid SCHEMBL9134833 | 0.89 | ADRB2 (0.48) | ADRB2ADRB1HTR1AADRA2ADRD2 | |
| SCHEMBL9501855 | 0.86 | ADRB2 (0.49) | ADRB2ADRB1HTR1AADRA2ADRD2 | |
| SCHEMBL9503443 | 0.86 | ADRB2 (0.49) | ADRB2ADRB1HTR1AADRA2ADRD2 | |
| SCHEMBL9503449 | 0.86 | ADRB2 (0.49) | ADRB2ADRB1HTR1AADRA2ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0549668-A1 | ANTI-HYPERTENSIVE TETRALINS | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-07-07 | — | — | EP | claimed |
| WO-1992005143-A1 | ANTI-HYPERTENSIVE TETRALINS | THE WELLCOME FOUNDATION LIMITED (GB) | 1992-04-02 | — | — | WO | claimed |