Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.81 |
| ▸ | RAB9A | P51151 | 2/20 | 0.81 |
| ▸ | HPGD | P15428 | 6/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31411480 | 0.90 | NPC1 (1.00) | NPC1RAB9AHPGDALDH1A1POLB | |
| SCHEMBL2344209 | 0.90 | NPC1 (1.00) | NPC1RAB9AHPGDALDH1A1POLB | |
| SCHEMBL881578 | 0.85 | NPC1 (0.58) | NPC1RAB9AHPGDALDH1A1POLB | |
| SCHEMBL6857852 | 0.84 | NPC1 (0.88) | NPC1RAB9AHPGDALDH1A1POLB | |
| SCHEMBL13430979 | 0.84 | NPC1 (0.67) | NPC1RAB9AHPGDALDH1A1POLB | |
| SCHEMBL25356036 | 0.82 | NPC1 (0.77) | NPC1RAB9AHPGDALDH1A1POLB | |
| SCHEMBL5475011 | 0.82 | POLB (0.68) | NPC1RAB9AHPGDALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL9004720 | 0.81 | POLB (0.66) | NPC1RAB9AHPGDALDH1A1POLB | |
| SCHEMBL30852954 | 0.80 | RAB9A (0.80) | NPC1RAB9AHPGDALDH1A1POLB | |
| SCHEMBL3723177 | 0.80 | RAB9A (0.80) | NPC1RAB9AHPGDALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0303988-B1 | POLYMER BOUND UV STABILIZERS | ATOCHEM NORTH AMERICA, INC. (US) | 1993-05-12 | — | — | EP | disclosed |
| US-5206378-A | Ultraviolet light stabilizers | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1993-04-27 | — | — | US | disclosed |
| EP-0303986-B1 | MULTIPURPOSE POLYMER BOUND STABILIZERS | ATOCHEM NORTH AMERICA, INC. (US) | 1992-07-29 | — | — | EP | disclosed |
| US-5096974-A | Reacting primary amino or hydrazido-substituted stabilizers with maleic anhydride polymers; nonextractable and nonvolatile in polymer blends | ATOCHEM NORTH AMERICA, INC. (US) | 1992-03-17 | — | — | US | disclosed |
| US-5096977-A | Anhydride polymers | ATOCHEM NORTH AMERICA, INC. (US) | 1992-03-17 | — | — | US | disclosed |
| US-4981915-A | HYDRAZIDE MODIFIERS | ATOCHEM NORTH AMERICA, INC. (US) | 1991-01-01 | — | — | US | disclosed |
| US-4981914-A | HYDRAZIDE MODIFIERS | ATOCHEM NORTH AMERICA, INC. (US) | 1991-01-01 | — | — | US | disclosed |
| US-4868246-A | PRIMARY AMINO OR HYDRAZIDO UV ABSORBERS CHEMICALLY BOUND TO POLYMER ANHYDRIDE GROUPS | PENNWALT CORPORATION (US) | 1989-09-19 | — | — | US | disclosed |
| US-4863999-A | IMIDES OR AMIC ACIDS OF ANHDRIDE POLYMERS | PENNWALT CORPORATION (US) | 1989-09-05 | — | — | US | disclosed |
| EP-0303988-A2 | Polymer bound UV stabilizers | ATOCHEM NORTH AMERICA, INC. (US) | 1989-02-22 | — | — | EP | disclosed |
| EP-0303986-A2 | Multipurpose polymer bound stabilizers | ATOCHEM NORTH AMERICA, INC. (US) | 1989-02-22 | — | — | EP | disclosed |