Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | PTGES | O14684 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | NPY1R | P25929 | 1/20 | 0.40 |
| ▸ | NPY2R | P49146 | 1/20 | 0.40 |
| ▸ | NPY4R | P50391 | 1/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8523784 | 0.80 | PTGS1 (0.61) | MRGPRX1CYP19A1PTGS1PTGS2ALDH1A1 | |
| SCHEMBL9502723 | 0.78 | CYP19A1 (0.73) | CYP19A1PTGS1PTGS2ALDH1A1KMT2A | |
| SCHEMBL9511659 | 0.77 | MRGPRX1 (0.47) | MRGPRX1CYP19A1PTGS1PTGS2ALDH1A1 | |
| SCHEMBL20022642 | 0.77 | NPY1R (0.50) | ALDH1A1KMT2ASMN1; SMN2MEN1TSHR | |
| SCHEMBL9501603 | 0.76 | PTGS2 (0.43) | MRGPRX1CYP19A1PTGS1PTGS2ALDH1A1 | |
| SCHEMBL1496601 | 0.73 | NPY1R (0.47) | ALDH1A1KMT2AMEN1CYP2D6NPY1R | |
| SCHEMBL9501963 | 0.72 | CYP19A1 (0.47) | MRGPRX1CYP19A1PTGS1PTGS2ALDH1A1 | |
| SCHEMBL1496734 | 0.72 | NPY1R (0.46) | KMT2AMEN1NPY1RNPY2RNPY4R | |
| SCHEMBL6378390 | 0.70 | PTGS1 (0.56) | CYP19A1PTGS1PTGS2ALDH1A1KMT2A | |
| SCHEMBL1496646 | 0.70 | NPY1R (0.44) | ALDH1A1KMT2AMEN1CYP2D6NPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0317332-B1 | SULFONANILIDE COMPOUNDS | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1993-05-19 | — | — | EP | disclosed |
| US-4885367-A | ANTIINFLAMMATORY AGENTS, ANTIPYRETICS, ANALGESICS; SIDE EFFECT REDUCTION | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1989-12-05 | — | — | US | disclosed |
| EP-0317332-A2 | Sulfonanilide compounds | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1989-05-24 | — | — | EP | disclosed |