Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 5/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | HRH1 | P35367 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9503443 | 1.00 | ADRB2 (0.49) | ADRB2ADRB1ADRA1AHTR1AADRA2A | |
| SCHEMBL9503449 | 1.00 | ADRB2 (0.49) | ADRB2ADRB1ADRA1AHTR1AADRA2A | |
| SCHEMBL9501859 | 1.00 | ADRB2 (0.49) | ADRB2ADRB1ADRA1AHTR1AADRA2A | |
| SCHEMBL9501855 | 1.00 | ADRB2 (0.49) | ADRB2ADRB1ADRA1AHTR1AADRA2A | |
| Hydrochloric Acid SCHEMBL9134505 | 0.99 | ADRB2 (0.49) | ADRB2ADRB1ADRA1AHTR1AADRA2A | |
| Hydrochloric Acid SCHEMBL9134508 | 0.99 | ADRB2 (0.49) | ADRB2ADRB1ADRA1AHTR1AADRA2A | |
| Hydrochloric Acid SCHEMBL9135276 | 0.99 | ADRB2 (0.49) | ADRB2ADRB1ADRA1AHTR1AADRA2A | |
| Hydrochloric Acid SCHEMBL9135272 | 0.99 | ADRB2 (0.49) | ADRB2ADRB1ADRA1AHTR1AADRA2A | |
| Hydrochloric Acid SCHEMBL9133808 | 0.99 | ADRB2 (0.49) | ADRB2ADRB1ADRA1AHTR1AADRA2A | |
| SCHEMBL9505712 | 0.88 | ADRB2 (0.49) | ADRB2ADRB1ADRA1AHTR1AADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0549668-A1 | ANTI-HYPERTENSIVE TETRALINS | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-07-07 | — | — | EP | claimed |
| WO-1992005143-A1 | ANTI-HYPERTENSIVE TETRALINS | THE WELLCOME FOUNDATION LIMITED (GB) | 1992-04-02 | — | — | WO | claimed |