SCHEMBL950354

SCHEMBL950354

FC(F)(F)Sc1cc[nH]n1

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15357748 0.77 KDM4E (0.31) KDM4E
SCHEMBL28552256 0.73
SCHEMBL18702480 0.72
SCHEMBL154871 0.72 EHMT2 (0.31)
Phosphine SCHEMBL27645652 0.70
SCHEMBL951220 0.69
SCHEMBL25572 0.69
SCHEMBL8838233 0.69
SCHEMBL3203798 0.69
SCHEMBL28723523 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-221889890-U Safety synthesizer for trifluoro methylthio pyrazole 江苏优普生物化学科技股份有限公司 2024-10-25 CN claimed
CN-112782313-A Liquid chromatography detection method of fipronil 扬州天和药业有限公司 2021-05-11 CN claimed
CN-112430213-A Synthesis process of trifluoromethylthio pyrazole 江苏优普生物化学科技股份有限公司 2021-03-02 CN claimed
CN-221889890-U Safety synthesizer for trifluoro methylthio pyrazole 江苏优普生物化学科技股份有限公司 2024-10-25 CN disclosed
CN-221889890-U Safety synthesizer for trifluoro methylthio pyrazole 江苏优普生物化学科技股份有限公司 2024-10-25 CN disclosed
CN-221889890-U Safety synthesizer for trifluoro methylthio pyrazole 江苏优普生物化学科技股份有限公司 2024-10-25 CN disclosed
CN-112782313-A Liquid chromatography detection method of fipronil 扬州天和药业有限公司 2021-05-11 CN disclosed
CN-112430213-A Synthesis process of trifluoromethylthio pyrazole 江苏优普生物化学科技股份有限公司 2021-03-02 CN disclosed
CN-112430213-A Synthesis process of trifluoromethylthio pyrazole 江苏优普生物化学科技股份有限公司 2021-03-02 CN disclosed
CN-112430213-A Synthesis process of trifluoromethylthio pyrazole 江苏优普生物化学科技股份有限公司 2021-03-02 CN disclosed
CN-111018786-A Production method of aryl pyrazole nitrile 江苏优普生物化学科技股份有限公司 2020-04-17 CN disclosed
WO-2007043677-A1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-04-19 WO disclosed
WO-2007043677-A1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-04-19 WO disclosed
US-6545033-B1 GABA receptor inhibitors 3-DIMENSIONAL PHARMACEUTICALS, INC. 2003-04-08 US disclosed
EP-1063992-A4 SULFURPENTA FLUOROPHENYL PYRAZOLES FOR CONTROLLING ECTOPARASITIC INFESTATIONS MERCK & CO INC (US) 2002-12-18 EP disclosed
EP-1063992-A1 SULFURPENTA FLUOROPHENYL PYRAZOLES FOR CONTROLLING ECTOPARASITIC INFESTATIONS Merck & Co., Inc. (US) 2001-01-03 EP disclosed
WO-1999047139-A1 SULFURPENTA FLUOROPHENYL PYRAZOLES FOR CONTROLLING ECTOPARASITIC INFESTATIONS MERCK & CO., INC. (US) 1999-09-23 WO disclosed
EP-0553119-A1 HETEROCYCLIC COMPOUNDS ZENECA LIMITED (GB) 1993-08-04 EP disclosed
WO-1992006964-A1 HETEROCYCLIC COMPOUNDS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1992-04-30 WO disclosed
EP-0398499-A2 Insecticides ZENECA LIMITED (GB) 1990-11-22 EP disclosed