Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 4/20 | 0.57 |
| ▸ | CYSLTR1 | Q9Y271 | 4/20 | 0.57 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 4/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.39 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 3/20 | 0.39 |
| ▸ | GLS | O94925 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9357158 | 0.93 | CYSLTR2 (0.48) | CYSLTR2CYSLTR1MGLLFAAHCYP4A11 | |
| SCHEMBL9357156 | 0.93 | CYSLTR2 (0.48) | CYSLTR2CYSLTR1MGLLFAAHCYP4A11 | |
| SCHEMBL9369239 | 0.92 | CYSLTR2 (0.48) | CYSLTR2CYSLTR1MGLLFAAHCYP4A11 | |
| SCHEMBL9356626 | 0.92 | CYSLTR2 (0.48) | CYSLTR2CYSLTR1MGLLFAAHCYP4A11 | |
| SCHEMBL9856680 | 0.89 | CYSLTR2 (0.46) | CYSLTR2CYSLTR1MGLLFAAHCYP4A11 | |
| SCHEMBL9364884 | 0.88 | CYSLTR2 (0.62) | CYSLTR2CYSLTR1 | |
| SCHEMBL9364882 | 0.88 | CYSLTR2 (0.62) | CYSLTR2CYSLTR1 | |
| SCHEMBL9429346 | 0.86 | CYSLTR2 (0.43) | CYSLTR2CYSLTR1MGLLFAAHCYP4A11 | |
| SCHEMBL9427991 | 0.85 | CYSLTR2 (0.64) | CYSLTR2CYSLTR1 | |
| SCHEMBL9364198 | 0.83 | CYSLTR2 (0.64) | CYSLTR2CYSLTR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0296732-B1 | LEUKOTRIENE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1991-10-09 | — | — | EP | claimed |
| EP-0375348-B1 | LEUKOTRIENE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-06-23 | — | — | EP | disclosed |