Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 4/20 | 0.62 |
| ▸ | CYSLTR1 | Q9Y271 | 4/20 | 0.62 |
| ▸ | PLA2G4B | P0C869 | 3/20 | 0.43 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.43 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.43 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.43 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.42 |
| ▸ | BID | P55957 | 1/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9364884 | 1.00 | CYSLTR2 (0.62) | CYSLTR2CYSLTR1PLA2G4BPLA2G4APTGER1 | |
| SCHEMBL9427991 | 0.90 | CYSLTR2 (0.64) | CYSLTR2CYSLTR1BIDBCL2L1MCL1 | |
| SCHEMBL9503595 | 0.88 | CYSLTR2 (0.57) | CYSLTR2CYSLTR1 | |
| SCHEMBL9428428 | 0.88 | CYSLTR2 (0.59) | CYSLTR2CYSLTR1BIDBCL2L1MCL1 | |
| SCHEMBL9364194 | 0.88 | CYSLTR2 (0.64) | CYSLTR2CYSLTR1BIDBCL2L1MCL1 | |
| SCHEMBL9364198 | 0.88 | CYSLTR2 (0.64) | CYSLTR2CYSLTR1BIDBCL2L1MCL1 | |
| SCHEMBL9428622 | 0.86 | CYSLTR2 (0.69) | CYSLTR2CYSLTR1PLA2G4BPTGER1PTGER4 | |
| SCHEMBL9364503 | 0.85 | CYSLTR2 (0.47) | CYSLTR2CYSLTR1PLA2G4BPLA2G4APTGER1 | |
| SCHEMBL8937745 | 0.85 | CYSLTR2 (0.47) | CYSLTR2CYSLTR1PLA2G4BPLA2G4APTGER1 | |
| SCHEMBL9502590 | 0.84 | CYSLTR2 (0.47) | CYSLTR2CYSLTR1PLA2G4BPLA2G4APTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0403249-B1 | Leukotriene antagonists | SMITHKLINE BEECHAM CORP (US) | 1994-04-27 | — | — | EP | disclosed |