Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | CCR5 | P51681 | 1/20 | 0.48 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3468096 | 0.83 | F2RL1 (0.63) | MAPTNPSR1ALDH1A1RXFP1POLB | |
| SCHEMBL9322885 | 0.82 | NPC1 (0.56) | MAPTHTTNPSR1ALDH1A1CYP2C9 | |
| SCHEMBL16516703 | 0.81 | MAPT (0.47) | MAPTHTTNPSR1ALDH1A1CYP2C9 | |
| SCHEMBL5355607 | 0.81 | MRGPRX4 (0.51) | MEN1KMT2A | |
| SCHEMBL6375687 | 0.79 | MAPT (0.96) | MAPTHTTNPSR1ALDH1A1CYP2C9 | |
| SCHEMBL1445627 | 0.79 | F2RL1 (0.73) | MAPTHTTALDH1A1POLBNPC1 | |
| SCHEMBL31432825 | 0.79 | ALOX5 (0.47) | MEN1KMT2A | |
| SCHEMBL3940302 | 0.77 | KMT2A (0.59) | MAPTALDH1A1POLBMEN1KMT2A | |
| SCHEMBL11136744 | 0.76 | MAPT (0.50) | MAPTHTTNPSR1ALDH1A1POLB | |
| SCHEMBL30175027 | 0.76 | KMT2A (0.53) | MAPTHTTNPSR1POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0331073-B1 | BENZHYDRYLAMINE DERIVATIVES | Chugai Seiyaku Kabushiki Kaisha (JP) | 1993-07-28 | — | — | EP | disclosed |
| US-5051526-A | Reagents for solid phase synthesis of polypeptides | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1991-09-24 | — | — | US | disclosed |
| US-4965405-A | INTERMEDIATE FOR POLYPEPTIDE SYNTHESIS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1990-10-23 | — | — | US | disclosed |
| EP-0331073-A2 | Benzhydrylamine derivatives | Chugai Seiyaku Kabushiki Kaisha (JP) | 1989-09-06 | — | — | EP | disclosed |