Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.54 |
| ▸ | CNR1 | P21554 | 4/20 | 0.53 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | MTOR | P42345 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9503796 | 1.00 | GAA (0.59) | GAATDP1L3MBTL1EPHX2CNR1 | |
| SCHEMBL9505521 | 0.94 | GAA (0.67) | GAATDP1L3MBTL1EPHX2CYP1A2 | |
| SCHEMBL9502190 | 0.87 | GAA (0.64) | GAATDP1L3MBTL1EPHX2TP53 | |
| SCHEMBL9503127 | 0.87 | GAA (0.64) | GAATDP1L3MBTL1EPHX2CNR1 | |
| SCHEMBL9502168 | 0.87 | GAA (0.64) | GAATDP1L3MBTL1EPHX2CNR1 | |
| SCHEMBL9502155 | 0.87 | GAA (0.64) | GAATDP1L3MBTL1EPHX2CNR1 | |
| SCHEMBL9503122 | 0.87 | GAA (0.64) | GAATDP1L3MBTL1EPHX2CNR1 | |
| SCHEMBL9502358 | 0.86 | GAA (0.63) | GAATDP1L3MBTL1EPHX2CNR1 | |
| SCHEMBL9502351 | 0.86 | GAA (0.63) | GAATDP1L3MBTL1EPHX2CNR1 | |
| SCHEMBL9505430 | 0.84 | ACAT1 (0.62) | CNR1CYP1A2CYP2D6MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543865-A1 | BENZAMIDE DERIVATIVES | RHONE-POULENC RORER LIMITED (GB) | 1993-06-02 | — | — | EP | disclosed |
| WO-1992003412-A2 | BENZAMIDE DERIVATIVES | RHONE-POULENC RORER LIMITED (GB) | 1992-03-05 | — | — | WO | disclosed |