Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.40 |
| ▸ | TSHR | P16473 | 5/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 4/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.31 |
| ▸ | PKM | P14618 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.30 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9191220 | 0.91 | TSHR (0.42) | ALDH1A1TSHRMAPK1SMN1; SMN2TDP1 | |
| SCHEMBL9191858 | 0.91 | TSHR (0.42) | ALDH1A1TSHRMAPK1SMN1; SMN2TDP1 | |
| SCHEMBL169656 | 0.91 | TSHR (0.42) | ALDH1A1TSHRMAPK1SMN1; SMN2TDP1 | |
| Trimethylammonium SCHEMBL9503885 | 0.83 | ALDH1A1 (0.38) | ALDH1A1TSHRMAPK1SMN1; SMN2TDP1 | |
| SCHEMBL9191856 | 0.73 | — | — | |
| SCHEMBL9191213 | 0.73 | — | — | |
| SCHEMBL27999107 | 0.73 | ALDH1A1 (0.40) | ALDH1A1TSHRMAPK1SMN1; SMN2TDP1 | |
| SCHEMBL169655 | 0.73 | — | — | |
| Propane SCHEMBL6827223 | 0.72 | SMN1; SMN2 (0.39) | ALDH1A1TSHRMAPK1SMN1; SMN2TDP1 | |
| Trimethylammonium SCHEMBL27470410 | 0.72 | TSHR (0.54) | ALDH1A1TSHRMAPK1SMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0187281-B1 | NOVEL CARBOXYLATE POLYMERS AND PROCESSES FOR THEIR PREPARATION AND USE | RHONE-POULENC SPECIALTY CHEMICALS CO. (US) | 1993-06-23 | — | — | EP | disclosed |
| US-4808668-A | SEWAGE TREATMENT FLOCCULANT | ALLIED-SIGNAL INC. (US) | 1989-02-28 | — | — | US | disclosed |
| EP-0187281-A2 | Novel carboxylate polymers and processes for their preparation and use | RHONE-POULENC SPECIALTY CHEMICALS CO. (US) | 1986-07-16 | — | — | EP | disclosed |