Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 16/20 | 0.59 |
| ▸ | CYSLTR1 | Q9Y271 | 16/20 | 0.59 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9503601 | 0.85 | CYSLTR2 (0.48) | CYSLTR2CYSLTR1EPHX2 | |
| SCHEMBL9160518 | 0.84 | CYSLTR2 (0.80) | CYSLTR2CYSLTR1 | |
| SCHEMBL9397875 | 0.84 | CYSLTR2 (0.80) | CYSLTR2CYSLTR1 | |
| SCHEMBL9559922 | 0.84 | CYSLTR2 (0.63) | CYSLTR2CYSLTR1 | |
| SCHEMBL9503582 | 0.83 | CYSLTR2 (0.72) | CYSLTR2CYSLTR1 | |
| SCHEMBL10424952 | 0.81 | CYSLTR2 (0.60) | CYSLTR2CYSLTR1 | |
| SCHEMBL9506698 | 0.78 | CYSLTR2 (0.68) | CYSLTR2CYSLTR1 | |
| SCHEMBL9560120 | 0.75 | CYSLTR2 (0.74) | CYSLTR2CYSLTR1 | |
| SCHEMBL9155567 | 0.74 | CYSLTR2 (1.00) | CYSLTR2CYSLTR1 | |
| SCHEMBL9155578 | 0.74 | CYSLTR2 (1.00) | CYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0375348-B1 | LEUKOTRIENE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-06-23 | — | — | EP | disclosed |
| US-4954513-A | Leukotriene antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1990-09-04 | — | — | US | disclosed |
| EP-0375348-A1 | Leukotriene antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1990-06-27 | — | — | EP | disclosed |