Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 12/20 | 0.48 |
| ▸ | CYSLTR1 | Q9Y271 | 12/20 | 0.48 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9503928 | 0.85 | CYSLTR2 (0.59) | CYSLTR2CYSLTR1EPHX2 | |
| SCHEMBL9503588 | 0.84 | CYSLTR2 (0.46) | CYSLTR2CYSLTR1LARS1PPARAEPHX2 | |
| SCHEMBL10431544 | 0.78 | CYSLTR2 (0.47) | CYSLTR2CYSLTR1 | |
| SCHEMBL9507512 | 0.77 | CYSLTR2 (0.46) | CYSLTR2CYSLTR1LARS1PPARAEPHX2 | |
| SCHEMBL9504777 | 0.76 | CYSLTR2 (0.57) | CYSLTR2CYSLTR1LARS1 | |
| SCHEMBL9484597 | 0.74 | CYSLTR2 (0.63) | CYSLTR2CYSLTR1PPARAS1PR2S1PR1 | |
| SCHEMBL19119201 | 0.74 | CYSLTR2 (0.63) | CYSLTR2CYSLTR1PPARAS1PR2S1PR1 | |
| SCHEMBL9160518 | 0.74 | CYSLTR2 (0.80) | CYSLTR2CYSLTR1 | |
| SCHEMBL9397875 | 0.74 | CYSLTR2 (0.80) | CYSLTR2CYSLTR1 | |
| SCHEMBL9560197 | 0.74 | CYSLTR2 (0.65) | CYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0375348-B1 | LEUKOTRIENE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-06-23 | — | — | EP | disclosed |
| US-4954513-A | Leukotriene antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1990-09-04 | — | — | US | disclosed |
| EP-0375348-A1 | Leukotriene antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1990-06-27 | — | — | EP | disclosed |