Sugi Predict

Sugi Predict / Compounds / Biphenyl

Biphenyl

Biphenyl

SCHEMBL9503944

CC(P)P.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 2/20 0.60
▸ PTGS2 P35354 1/20 0.46
▸ ATM Q13315 1/20 0.46
▸ SLC22A2 O15244 1/20 0.46
▸ SLC22A1 O15245 1/20 0.46
▸ SLC22A3 O75751 1/20 0.46
▸ SLC6A4 P31645 1/20 0.46
▸ TAAR1 Q96RJ0 2/20 0.44
▸ NPC1 O15118 1/20 0.43
▸ NFKB1 P19838 1/20 0.43
▸ RAB9A P51151 1/20 0.43
▸ NFKB2 Q00653 1/20 0.43
▸ RELA Q04206 1/20 0.43
▸ SMN1; SMN2 Q16637 1/20 0.43
▸ CYP1A2 P05177 2/20 0.43
▸ MAPK1 P28482 1/20 0.43
▸ CYP3A4 P08684 1/20 0.43
▸ HSD17B10 Q99714 1/20 0.43
▸ TDP1 Q9NUW8 1/20 0.43
▸ NOTUM Q6P988 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL3105248 0.93 ALDH1A1 (0.60) ALDH1A1PTGS2SLC22A2SLC22A1SLC22A3
Biphenyl SCHEMBL27941989 0.90 ALDH1A1 (0.56) ALDH1A1PTGS2SLC22A2SLC22A1SLC22A3
Biphenyl SCHEMBL27941990 0.90 ALDH1A1 (0.56) ALDH1A1PTGS2SLC22A2SLC22A1SLC22A3
Biphenyl SCHEMBL27656690 0.86 ALDH1A1 (0.69) ALDH1A1PTGS2ATMSLC22A2SLC22A1
Biphenyl SCHEMBL27941894 0.83 ALDH1A1 (0.47) ALDH1A1PTGS2SLC22A2SLC22A1SLC22A3
Biphenyl SCHEMBL27941858 0.83 ALDH1A1 (0.47) ALDH1A1PTGS2SLC22A2SLC22A1SLC22A3
Biphenyl SCHEMBL27941891 0.83 ALDH1A1 (0.47) ALDH1A1PTGS2SLC22A2SLC22A1SLC22A3
Biphenyl SCHEMBL27941859 0.83 ALDH1A1 (0.47) ALDH1A1PTGS2SLC22A2SLC22A1SLC22A3
Biphenyl SCHEMBL27519887 0.83 ALDH1A1 (0.64) ALDH1A1PTGS2SLC22A2SLC22A1SLC22A3
Biphenyl SCHEMBL2136748 0.82 ALDH1A1 (0.75) ALDH1A1ATMSLC22A2SLC22A1SLC22A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0395144-B1 A PROCESS FOR THE PREPARATION OF AROMATIC UREAS SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1993-06-30 — — EP disclosed
EP-0395144-A1 A process for the preparation of aromatic ureas SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1990-10-31 — — EP disclosed
EP-0393789-A1 A process for the preparation of carbamates SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1990-10-24 — — EP disclosed
EP-0225673-B1 PROCESS FOR THE PREPARATION OF ACYL UREAS SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1989-10-25 — — EP disclosed
EP-0319111-A2 Process for the preparation of phenyl ureas SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1989-06-07 — — EP disclosed
EP-0086281-B2 PREPARATION OF CARBAMATES USING A PALLADIUM-CONTAINING CATALYST SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1988-10-19 — — EP disclosed
EP-0225673-A1 Process for the preparation of acyl ureas SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1987-06-16 — — EP disclosed
EP-0086281-B1 PREPARATION OF CARBAMATES USING A PALLADIUM-CONTAINING CATALYST SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1985-05-15 — — EP disclosed
US-4474978-A Preparation of carbamates SHELL OIL COMPANY (US) 1984-10-02 — — US disclosed
EP-0086281-A1 Preparation of carbamates using a palladium-containing catalyst SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1983-08-24 — — EP disclosed