Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 2/20 | 0.76 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | RAD52 | P43351 | 1/20 | 0.64 |
| ▸ | RECQL | P46063 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.64 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.63 |
| ▸ | HEXA | P06865 | 3/20 | 0.60 |
| ▸ | HEXB | P07686 | 3/20 | 0.60 |
| ▸ | OGA | O60502 | 1/20 | 0.60 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.59 |
| ▸ | NGFR | P08138 | 1/20 | 0.59 |
| ▸ | CA12 | O43570 | 3/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12502144 | 0.98 | FTO (0.75) | FTOPABPC1MEN1KMT2APOLB | |
| SCHEMBL8622765 | 0.97 | FTO (0.77) | FTOPABPC1MEN1KMT2APOLB | |
| SCHEMBL9501837 | 0.95 | FTO (0.82) | FTOPABPC1MEN1KMT2APOLB | |
| SCHEMBL8984579 | 0.94 | FTO (0.80) | FTOPABPC1MEN1KMT2APOLB | |
| SCHEMBL12660530 | 0.93 | FTO (0.69) | FTOPABPC1MEN1KMT2APOLB | |
| SCHEMBL12660529 | 0.92 | FTO (0.71) | FTOPABPC1MEN1KMT2APOLB | |
| Hydrochloric Acid SCHEMBL5747370 | 0.91 | FTO (0.72) | FTOPABPC1MEN1KMT2APOLB | |
| SCHEMBL3854336 | 0.89 | FTO (0.87) | FTOPABPC1MEN1KMT2APOLB | |
| SCHEMBL26773419 | 0.89 | FTO (0.76) | FTOPABPC1MEN1KMT2APOLB | |
| SCHEMBL8984832 | 0.88 | FTO (0.74) | FTOPABPC1MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0281902-B1 | BIS-NAPHTHALIMIDES, THEIR PREPARATION AND USE | KNOLL AG (DE) | 1993-06-09 | — | — | EP | disclosed |
| US-4874863-A | Bisnaphthalimides | KNOLL AG (DE) | 1989-10-17 | — | — | US | disclosed |
| EP-0281902-A1 | Bis-naphthalimides, their preparation and use | KNOLL AG (DE) | 1988-09-14 | — | — | EP | disclosed |