Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.80 |
| ▸ | MAOB | P27338 | 4/20 | 0.52 |
| ▸ | MAOA | P21397 | 3/20 | 0.52 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PNMT | P11086 | 1/20 | 0.43 |
| ▸ | CD44 | P16070 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | DRD5 | P21918 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.40 |
| ▸ | BAD | Q92934 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL28831559 | 0.97 | TSHR (0.75) | TSHRMAOBMAOACYP2A6HTR2C | |
| SCHEMBL451157 | 0.96 | TSHR (0.86) | TSHRMAOBMAOACYP2A6HTR2C | |
| SCHEMBL3057782 | 0.96 | TSHR (0.86) | TSHRMAOBMAOACYP2A6HTR2C | |
| SCHEMBL9662 | 0.96 | — | — | |
| SCHEMBL29354295 | 0.96 | — | — | |
| Methane SCHEMBL19946467 | 0.93 | TSHR (0.80) | TSHRMAOBMAOACYP2A6HTR2C | |
| Ammonia Solution, Strong SCHEMBL6332955 | 0.93 | TSHR (0.80) | TSHRMAOBMAOACYP2A6HTR2C | |
| Water SCHEMBL7121211 | 0.93 | TSHR (0.80) | TSHRMAOBMAOACYP2A6HTR2C | |
| Ammonia Solution, Strong SCHEMBL1151087 | 0.93 | TSHR (0.80) | TSHRMAOBMAOACYP2A6HTR2C | |
| SCHEMBL8676208 | 0.93 | TSHR (0.80) | TSHRMAOBMAOACYP2A6HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114080432-B | Ink and ink jet recording method | 日本化药株式会社 | 2023-03-28 | — | — | CN | disclosed |
| CN-114080432-A | Ink and ink jet recording method | 日本化药株式会社 | 2022-02-22 | — | — | CN | disclosed |
| CN-113348175-A | Flame retardant and preparation method thereof | 罗地亚经营管理公司 | 2021-09-03 | — | — | CN | disclosed |
| EP-0331147-B1 | COATING COMPOSITIONS AND METHODS FOR PREVENTING ADHESION OF ORGANISMS | KANSAI PAINT CO., LTD. (JP) | 1993-08-04 | — | — | EP | disclosed |
| US-5015472-A | Antideposit agents, antifouling agents, protective coatings | KANSAI PAINT CO., LTD. (JP) | 1991-05-14 | — | — | US | disclosed |
| US-4973477-A | UNDERWATER STRUCTURES, FUNGICIDES, RELEASES PHENOL | KANSAI PAINT COMPANY, LIMITED (JP) | 1990-11-27 | — | — | US | disclosed |
| EP-0331147-A2 | Coating compositions and methods for preventing adhesion of organisms | KANSAI PAINT CO., LTD. (JP) | 1989-09-06 | — | — | EP | disclosed |