Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL659708 | 0.79 | TSHR (0.52) | TSHRCYP1A2ALDH1A1KCNN4ALOX15 | |
| SCHEMBL28399440 | 0.78 | TSHR (0.46) | TSHRCYP1A2ALDH1A1KCNN4ALOX15 | |
| SCHEMBL3052236 | 0.78 | TSHR (0.46) | TSHRCYP1A2ALDH1A1KCNN4CYP2D6 | |
| SCHEMBL29092906 | 0.78 | TSHR (0.50) | TSHRLMNAKMT2A | |
| SCHEMBL28342294 | 0.75 | CYP1A2 (0.50) | TSHRCYP1A2ALDH1A1KCNN4CNR1 | |
| SCHEMBL5459793 | 0.73 | TSHR (0.46) | TSHRCYP1A2ALDH1A1KCNN4CNR1 | |
| SCHEMBL11133348 | 0.73 | ALDH1A1 (0.43) | TSHRCYP1A2ALDH1A1KCNN4ALOX15 | |
| SCHEMBL8089565 | 0.72 | TSHR (0.50) | TSHRCYP1A2ALDH1A1KCNN4ALOX15 | |
| SCHEMBL16680333 | 0.72 | CYP1A2 (0.42) | TSHRCYP1A2ALDH1A1PTPN1CNR1 | |
| SCHEMBL29180618 | 0.70 | KCNN4 (0.41) | TSHRCYP1A2ALDH1A1KCNN4CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115702234-A | Environment-friendly solvent, and washing composition and washing device comprising same | 株式会社LG生活健康 | 2023-02-14 | — | — | CN | disclosed |
| CN-115701977-A | Composition for treating hair or fiber comprising alkylketene compound | 株式会社LG生活健康 | 2023-02-14 | — | — | CN | disclosed |
| EP-0458823-B1 | A PROCESS FOR PREPARATION OF ENANTIOMERICALLY PURE POLYSUBSTITUTED 1,4-DIHYDROPYRIDINES | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1993-10-13 | — | — | EP | disclosed |
| US-5245039-A | PROCESS FOR PREPARATION OF ENANTIOMERICALLY PURE POLYSUBSTITUTED 1,4-DIHYDROPYRIDINES | BOEHRINGER MANNHEIM ITALIA (IT) | 1993-09-14 | — | — | US | disclosed |
| WO-1990009376-A1 | A PROCESS FOR PREPARATION OF ENANTIOMERICALLY PURE POLYSUBSTITUTED 1,4-DIHYDROPYRIDINES | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1990-08-23 | — | — | WO | disclosed |
| EP-0383320-A1 | A process for preparation of enantiomerically pure polysubstituted 1,4-dihydropyridines | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1990-08-22 | — | — | EP | disclosed |