SCHEMBL9504312

SCHEMBL9504312

CCCCCCCCSC(=O)CC

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 6/20 0.50
HSD17B10 Q99714 2/20 0.50
GMNN O75496 1/20 0.50
TP53 P04637 1/20 0.50
POLB P06746 1/20 0.50
MAPT P10636 1/20 0.50
THRB P10828 1/20 0.50
CYP2C9 P11712 1/20 0.50
BLM P54132 1/20 0.50
TSHR P16473 3/20 0.46
ALDH1A1 P00352 2/20 0.46
ACHE P22303 3/20 0.46
EPHX1 P07099 1/20 0.45
CES1 P23141 7/20 0.44
FAAH O00519 4/20 0.44
PLA2G6 O60733 1/20 0.44
PPARG P37231 3/20 0.42
PPARD Q03181 3/20 0.42
PPARA Q07869 3/20 0.42
GPR84 Q9NQS5 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3683268 1.00 CES2 (0.50) CES2HSD17B10GMNNTP53POLB
SCHEMBL11441143 1.00 CES2 (0.50) CES2HSD17B10GMNNTP53POLB
SCHEMBL7804794 1.00 CES2 (0.50) CES2HSD17B10GMNNTP53POLB
Methane SCHEMBL3725723 0.98 CES2 (0.48) CES2HSD17B10GMNNTP53POLB
SCHEMBL15615683 0.97 CES2 (0.46) CES2HSD17B10GMNNTP53POLB
SCHEMBL11543202 0.93 CES2 (0.45) CES2HSD17B10GMNNTP53POLB
SCHEMBL11544411 0.93 CES2 (0.45) CES2HSD17B10GMNNTP53POLB
SCHEMBL13135021 0.92 TDP1 (0.42) CES2HSD17B10GMNNTP53POLB
SCHEMBL6234311 0.90
SCHEMBL11437360 0.89 CES2 (0.42) CES2HSD17B10GMNNTP53POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0413562-B1 S-ALKYLTHIOPROPIONIC ACIDS AND DERIVATIVES WITCO CORPORATION (US) 1993-09-01 EP disclosed
EP-0413563-B1 SOLVENT REFINING ALKYLTHIOPROPIONIC PENTAERYTHRITOL ESTERS WITCO CORPORATION (US) 1993-09-01 EP disclosed
US-5198486-A Polymer stabilizers WITCO CORPORATION (US) 1993-03-30 US disclosed
US-5057622-A From alkyl mercaptan and acrylic acid WITCO CORPORATION (US) 1991-10-15 US disclosed
US-5055606-A Dissolving in and recrystallizing from mixture of lower aliphatic alcohol and lower aliphatic acid ester WITCO CORPORATION (US) 1991-10-08 US disclosed
EP-0413563-A1 Solvent refining alkylthiopropionic pentaerythritol esters WITCO CORPORATION (US) 1991-02-20 EP disclosed
EP-0413562-A1 S-alkylthiopropionic acids and derivatives WITCO CORPORATION (US) 1991-02-20 EP disclosed