Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.47 |
| ▸ | TLR4 | O00206 | 1/20 | 0.45 |
| ▸ | TLR2 | O60603 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1340780 | 0.84 | NPC1 (0.60) | TDP1CYP19A1KMT2AL3MBTL1SMN1; SMN2 | |
| SCHEMBL11219604 | 0.80 | ALDH1A1 (0.55) | TDP1KMT2AL3MBTL1SMN1; SMN2TSHR | |
| SCHEMBL29938739 | 0.80 | CYP19A1 (0.50) | TDP1CYP19A1TLR4TLR2L3MBTL1 | |
| SCHEMBL3803035 | 0.78 | NPC1 (0.64) | TDP1KMT2AL3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL2413642 | 0.77 | NPC1 (0.41) | CYP19A1TLR4TLR2KMT2ASMN1; SMN2 | |
| SCHEMBL10502417 | 0.77 | RECQL (0.46) | TDP1CYP19A1TLR4TLR2KMT2A | |
| SCHEMBL12261485 | 0.77 | CYP19A1 (0.50) | TDP1CYP19A1TLR4TLR2KMT2A | |
| SCHEMBL1341199 | 0.77 | ALDH1A1 (0.51) | CYP19A1KMT2AL3MBTL1SMN1; SMN2TSHR | |
| SCHEMBL30072726 | 0.76 | TDP1 (0.60) | TDP1KMT2AL3MBTL1SMN1; SMN2TSHR | |
| SCHEMBL1141627 | 0.76 | TDP1 (0.60) | TDP1KMT2AL3MBTL1SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0279096-B1 | BENZYL ETHER COMPOUND AND PROCESS FOR PRODUCING THE SAME | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1993-07-07 | — | — | EP | claimed |