Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.53 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MME | P08473 | 2/20 | 0.44 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28654785 | 0.85 | RECQL (0.62) | RECQLCYP3A4CYP2C9AKR1C3MTNR1A | |
| SCHEMBL28946517 | 0.84 | CYP3A4 (0.58) | RECQLCYP3A4CYP2C9AKR1C3MTNR1A | |
| SCHEMBL166780 | 0.81 | RECQL (0.72) | RECQLCYP3A4CYP2C9AKR1C3MTNR1A | |
| SCHEMBL27158696 | 0.81 | RECQL (0.72) | RECQLCYP3A4CYP2C9AKR1C3MTNR1A | |
| SCHEMBL5032754 | 0.81 | RECQL (0.72) | RECQLCYP3A4CYP2C9AKR1C3MTNR1A | |
| SCHEMBL2224096 | 0.81 | RECQL (0.72) | RECQLCYP3A4CYP2C9AKR1C3MTNR1A | |
| Methacrylic Acid SCHEMBL10714804 | 0.81 | CYP3A4 (0.54) | RECQLCYP3A4CYP2C9AKR1C3MTNR1A | |
| SCHEMBL3191512 | 0.79 | CYP3A4 (0.56) | RECQLCYP3A4CYP2C9AKR1C3MTNR1A | |
| SCHEMBL9574030 | 0.79 | CYP3A4 (0.56) | RECQLCYP3A4CYP2C9AKR1C3MTNR1A | |
| SCHEMBL11558198 | 0.79 | CYP3A4 (0.56) | RECQLCYP3A4CYP2C9AKR1C3MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0383655-B1 | USE OF POLYDIORGANOSILOXANES WITH DIBENZOYLMETHANE FUNCTION IN COSMETICS AND COSMETIC COMPOSITIONS CONTAINING THESE COMPOUNDS FOR THE PROTECTION OF HAIR AND SKIN | L'OREAL (FR) | 1993-04-28 | — | — | EP | disclosed |
| EP-0335777-B1 | COSMETIC USE OF DIORGANOPOLYSILOXANES BEARING A 3-BENZYLIDENE-CAMPHOR FUNCTIONAL GROUP | L'OREAL (FR) | 1991-12-18 | — | — | EP | disclosed |
| US-4562278-A | SUNSCREEN AGENTS | DOW CORNING, LTD. (GB) | 1985-12-31 | — | — | US | disclosed |
| US-4558111-A | Method for preparing acrylic functional halosilanes and halosiloxanes | GENERAL ELECTRIC COMPANY (US) | 1985-12-10 | — | — | US | disclosed |
| EP-0138590-A2 | Organosilicon compounds and preparation and use thereof | Dow Corning Limited (GB) | 1985-04-24 | — | — | EP | disclosed |