Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11333254 | 0.83 | TGFBR1 (0.45) | TGFBR1ALDH1A1RXFP1TDP1KDM4E | |
| SCHEMBL5407761 | 0.78 | KDM4E (0.37) | ALDH1A1KDM4ETSHR | |
| SCHEMBL19583252 | 0.78 | TGFBR1 (0.45) | TGFBR1ALDH1A1RXFP1TDP1KDM4E | |
| SCHEMBL9807136 | 0.78 | TGFBR1 (0.45) | TGFBR1ALDH1A1RXFP1TDP1KDM4E | |
| SCHEMBL10690868 | 0.76 | TGFBR1 (0.53) | TGFBR1ALDH1A1RXFP1TDP1KDM4E | |
| SCHEMBL640988 | 0.75 | TGFBR1 (0.42) | TGFBR1ALDH1A1RXFP1TSHR | |
| SCHEMBL24333197 | 0.74 | TGFBR1 (0.50) | TGFBR1ALDH1A1RXFP1TDP1KDM4E | |
| SCHEMBL14951 | 0.74 | — | — | |
| SCHEMBL2487819 | 0.74 | TGFBR1 (0.50) | TGFBR1ALDH1A1RXFP1TDP1KDM4E | |
| SCHEMBL1820299 | 0.74 | TGFBR1 (0.50) | TGFBR1ALDH1A1RXFP1TDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0376094-B1 | PROCESS FOR HARDENING AN INJECTION AGENT | RÖHM GMBH (DE) | 1993-06-16 | — | — | EP | disclosed |