Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | ERN1 | O75460 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.41 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30343616 | 1.00 | POLB (0.50) | POLBMAOBERN1PTPN1MEN1 | |
| SCHEMBL32889344 | 0.86 | POLB (0.47) | POLBMAOBERN1PTPN1MEN1 | |
| SCHEMBL8188785 | 0.83 | POLB (0.50) | POLBMAOBCYP2A6TDP1ALDH1A1 | |
| SCHEMBL2783911 | 0.79 | POLB (0.50) | POLBMAOBCYP2A6TDP1ALDH1A1 | |
| SCHEMBL8188781 | 0.79 | POLB (0.50) | POLBMAOBCYP2A6TDP1ALDH1A1 | |
| SCHEMBL7643518 | 0.78 | DNMT1 (0.48) | POLBERN1PTPN1MEN1KMT2A | |
| SCHEMBL29521593 | 0.78 | DNMT1 (0.48) | POLBERN1PTPN1MEN1KMT2A | |
| SCHEMBL31620472 | 0.78 | CYP2A6 (0.49) | ERN1PTPN1CYP2A6ALDH1A1 | |
| SCHEMBL197337 | 0.77 | ERN1 (0.62) | POLBERN1PTPN1MEN1KMT2A | |
| SCHEMBL31663413 | 0.77 | ERN1 (0.62) | POLBERN1PTPN1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 277 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113214182-A | Benzisothiazole compound and preparation method thereof | 佛山湘潭大学绿色智造研究院 | 2021-08-06 | — | — | CN | claimed |
| CN-110372722-B | Method for synthesizing sulfur-nitrogen-containing bis-heterocyclic compound | 河南师范大学 | 2020-08-11 | — | — | CN | claimed |
| CN-106111190-B | A kind of chirality biaryl skeleton pyridoxamine class catalyst and its synthetic method and application | 上海师范大学 | 2019-03-08 | — | — | CN | claimed |
| CN-106111190-A | A kind of chirality biaryl skeleton pyridoxamine class catalyst and synthetic method thereof and application | 上海师范大学 | 2016-11-16 | — | — | CN | claimed |
| US-20100055562-A1 | NANOWIRE LAYER ADHESION ON A SUBSTRATE | SEOUL NATIONAL UNIVERSITY INDUSTRY FOUNDATION (KR) | 2010-03-04 | — | — | US | claimed |
| EP-0116454-A2 | Enhanced luminescent or luminometric assay | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1984-08-22 | — | — | EP | claimed |
| US-12610738-B2 | Organic electroluminescent compound and organic electroluminescent device comprising the same | DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) | 2026-04-21 | — | — | US | disclosed |
| CN-119677749-A | Azaquinazoline pan KRAS inhibitors | 米拉蒂治疗股份有限公司 | 2025-03-21 | — | — | CN | disclosed |
| US-12187681-B2 | Ion channel antagonists/blockers and uses thereof | SHANGHAI EAST HOSPITAL (CN) | 2025-01-07 | — | — | US | disclosed |
| US-12171137-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION | 2024-12-17 | — | — | US | disclosed |
| US-20240325572-A1 | N-HETEROCYCLYL SUBSTITUTED 2-CYANO-3-(NAPHTHALEN-2-YL)ACRYLAMIDE DERIVATIVES AS FLUOROPHORS FOR DETECTION OF AMYLOID AND AMYLOID-LIKE PROTEINS FOR DIAGNOSIS OF NEURODEGENERATIVE DISORDERS | Amydis, Inc. | 2024-10-03 | — | — | US | disclosed |
| CN-118666661-A | Alpha-hydroxy ketone long wavelength photoinitiator and preparation method and application thereof | 北京化工大学 | 2024-09-20 | — | — | CN | disclosed |
| US-12075695-B2 | Compound and organic light-emitting device comprising same | LG CHEM, LTD. (KR) | 2024-08-27 | — | — | US | disclosed |
| WO-1998022457-A9 | ARYL AND HETEROARYL SUBSTITUTED FUSED PYRROLE ANTIINFLAMMATORY AGENTS | — | 1998-08-20 | — | — | WO | disclosed |
| WO-1998022457-A1 | ARYL AND HETEROARYL SUBSTITUTED FUSED PYRROLE ANTIINFLAMMATORY AGENTS | AMGEN INC. (US) | 1998-05-28 | — | — | WO | disclosed |
| CN-1182428-A | Fused imidazo [1, 2-alpha ] pyridines | SHINNIPPON PHARMACEUTICAL INC (JP) | 1998-05-20 | — | — | CN | disclosed |
| EP-0822194-A1 | FUSED IMIDAZO 1,2-a]PYRIDINES | Shinnippon Pharmaceutical Inc. (JP) | 1998-02-04 | — | — | EP | disclosed |
| US-4060677-A | Process for molecular weight lowering of vinyl halide polymers employing saturated carbon to carbon bonded aldehydes | HOOKER CHEMICALS & PLASTICS CORPORATION (US) | 1977-11-29 | — | — | US | disclosed |
| US-4017313-A | Photosensitive composition containing a leuco dye, a photosensitizer, an aromatic aldehyde and a secondary or tertiary amine and the use thereof in a direct-print process | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1977-04-12 | — | — | US | disclosed |
| US-3940400-A | 3-Methyl-4-phenyl-1,2,3,4-tetrahydrobenz[g]isoquinoline hydrobromide | MORTON-NORWICH PRODUCTS, INC. (US) | 1976-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12171137-B2 | Organic electroluminescent materials and devices | OXGR1, NR2C2, OCIAD2 | POLB 4264/4885MAOB 1797/4885ERN1 1581/4885 |
| US-12610738-B2 | Organic electroluminescent compound and organic electroluminescent device comprising the same | RUVBL1, RPS10, RPS21 | POLB 1640/4885MAOB 3053/4885ERN1 212/4885 |
| US-12075695-B2 | Compound and organic light-emitting device comprising same | ARL1, AR, ALG3 | POLB 3554/4885MAOB 1207/4885ERN1 1591/4885 |
| US-12187681-B2 | Ion channel antagonists/blockers and uses thereof | CACNA1F, CACNA1S, CACNA1D | POLB 3830/4885MAOB 813/4885ERN1 4435/4885 |
| US-20240325572-A1 | N-HETEROCYCLYL SUBSTITUTED 2-CYANO-3-(NAPHTHALEN-2-YL)ACRYLAMIDE DERIVATIVES AS FLUOROPHORS FOR DETECTION OF AMYLOID AND AMYLOID-LIKE PROTEINS FOR DIAGNOSIS OF NEURODEGENERATIVE DISORDERS | TARDBP, CDR2, NLN | POLB 2238/4885MAOB 1241/4885ERN1 2552/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.