SCHEMBL9504533

SCHEMBL9504533

COc1ccccc1NC(=O)C(=O)NN

nearest known ligand 0.61

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.61
SMN1; SMN2 Q16637 2/20 0.61
KDM4E B2RXH2 1/20 0.61
NPC1 O15118 1/20 0.61
RAB9A P51151 1/20 0.61
POLB P06746 2/20 0.59
CASP6 P55212 1/20 0.59
TDP1 Q9NUW8 1/20 0.59
MAPT P10636 4/20 0.57
KMT2A Q03164 4/20 0.57
LMNA P02545 2/20 0.57
L3MBTL1 Q9Y468 1/20 0.57
GAA P10253 1/20 0.56
HTT P42858 1/20 0.56
HSD17B10 Q99714 1/20 0.54
KCNH2 Q12809 1/20 0.54
CTSD P07339 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6850954 0.91 ALDH1A1 (0.71) ALDH1A1SMN1; SMN2KDM4ENPC1RAB9A
SCHEMBL6855776 0.86 ALDH1A1 (0.65) ALDH1A1SMN1; SMN2KDM4ENPC1RAB9A
SCHEMBL10522681 0.85 ALDH1A1 (0.60) ALDH1A1SMN1; SMN2KDM4ENPC1RAB9A
SCHEMBL30233758 0.84 ALDH1A1 (0.66) ALDH1A1SMN1; SMN2KDM4ENPC1RAB9A
SCHEMBL9036508 0.84 ALDH1A1 (0.71) ALDH1A1SMN1; SMN2KDM4ENPC1RAB9A
SCHEMBL9291128 0.84 USP2 (0.59) ALDH1A1SMN1; SMN2KDM4ENPC1RAB9A
SCHEMBL20711481 0.83 GAA (0.62) ALDH1A1SMN1; SMN2KDM4ENPC1RAB9A
Hydrochloric Acid SCHEMBL9004628 0.83 ALDH1A1 (0.69) ALDH1A1SMN1; SMN2KDM4ENPC1RAB9A
SCHEMBL22431603 0.83 NPC1 (0.72) ALDH1A1SMN1; SMN2KDM4ENPC1RAB9A
SCHEMBL14394196 0.83 ALDH1A1 (0.61) ALDH1A1SMN1; SMN2KDM4ENPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0303988-B1 POLYMER BOUND UV STABILIZERS ATOCHEM NORTH AMERICA, INC. (US) 1993-05-12 EP disclosed
US-5206378-A Ultraviolet light stabilizers ELF ATOCHEM NORTH AMERICA, INC. (US) 1993-04-27 US disclosed
EP-0303986-B1 MULTIPURPOSE POLYMER BOUND STABILIZERS ATOCHEM NORTH AMERICA, INC. (US) 1992-07-29 EP disclosed
US-5096974-A Reacting primary amino or hydrazido-substituted stabilizers with maleic anhydride polymers; nonextractable and nonvolatile in polymer blends ATOCHEM NORTH AMERICA, INC. (US) 1992-03-17 US disclosed
US-5096977-A Anhydride polymers ATOCHEM NORTH AMERICA, INC. (US) 1992-03-17 US disclosed
US-4981915-A HYDRAZIDE MODIFIERS ATOCHEM NORTH AMERICA, INC. (US) 1991-01-01 US disclosed
US-4981914-A HYDRAZIDE MODIFIERS ATOCHEM NORTH AMERICA, INC. (US) 1991-01-01 US disclosed
US-4868246-A PRIMARY AMINO OR HYDRAZIDO UV ABSORBERS CHEMICALLY BOUND TO POLYMER ANHYDRIDE GROUPS PENNWALT CORPORATION (US) 1989-09-19 US disclosed
US-4863999-A IMIDES OR AMIC ACIDS OF ANHDRIDE POLYMERS PENNWALT CORPORATION (US) 1989-09-05 US disclosed
EP-0303986-A2 Multipurpose polymer bound stabilizers ATOCHEM NORTH AMERICA, INC. (US) 1989-02-22 EP disclosed