SCHEMBL9504629

SCHEMBL9504629

Clc1nc(Cl)c(C(Cl)(Cl)Cl)s1

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9509004 0.80
SCHEMBL9505542 0.80
SCHEMBL15292237 0.77 KMT2A (0.34) TSHR
SCHEMBL6810434 0.77
SCHEMBL4591310 0.65
SCHEMBL8806119 0.63 CYP3A4 (0.30) CYP3A4TSHR
SCHEMBL6050393 0.63
SCHEMBL10413165 0.61
SCHEMBL15751858 0.61
SCHEMBL20604371 0.60 PDK2 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4788208-A FUNGICIDES; INTERMEDIATES FOR HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 1988-11-29 US claimed
US-11369113-B2 Vector control compositions, methods and products utilizing same SYNGENTA PARTICIPATIONS AG (CH) 2022-06-28 US disclosed
US-11369113-B2 Vector control compositions, methods and products utilizing same SYNGENTA PARTICIPATIONS AG (CH) 2022-06-28 US disclosed
EP-3700893-B1 VECTOR CONTROL COMPOSITIONS, METHODS AND PRODUCTS UTILIZING SAME SYNGENTA PARTICIPATIONS AG (CH) 2021-11-17 EP disclosed
US-20200315175-A1 Vector Control Compositions, Methods And Products Utilizing Same SYNGENTA PARTICIPATIONS AG (CH) 2020-10-08 US disclosed
EP-0348737-B1 HETEROARYLOXY-ACETIC ACID N-ISOPROPYL ANILIDES BAYER AG (DE) 1993-08-04 EP disclosed
EP-0316731-B1 AZO DYES FROM 2-HYDRAZINOTHIAZOLE, THEIR USE IN DYEING AND PRINTING FIBRE MATERIALS, AND IN SUBLIMATION TRANSFER PRINTING BAYER AG (DE) 1993-05-19 EP disclosed
US-5090991-A HERBICIDAL N-ISOPROPYLHETEROARYLOXYACETANILIDES BAYER AKATIENGESELLSCHAFT (DE) 1992-02-25 US disclosed
US-4968342-A PRE-AND POSTEMERGENCE BAYER AKTIENGESELLSCHAFT (DE) 1990-11-06 US disclosed
US-4929743-A Novel 4,5-disubstituted 1,3-thiazol-2-yloxyacetamide herbicides BAYER AKTIENGESELLSCHAFT (DE) 1990-05-29 US disclosed
US-4910316-A Reacting 2,4-dichloro-5-thiazolecarboxaldehyde with thionyl chloride BAYER AKTIENGESELLSCHAFT (DE) 1990-03-20 US disclosed
EP-0348737-A1 Heteroaryloxy-acetic acid N-isopropyl anilides BAYER AG (DE) 1990-01-03 EP disclosed
EP-0316731-A2 Azo dyes from 2-hydrazinothiazole, their use in dyeing and printing fibre materials, and in sublimation transfer printing BAYER AG (DE) 1989-05-24 EP disclosed
EP-0308740-A1 Process for the preparation of 2,4-dichloro-5-dichloromethyl thiazole BAYER AG (DE) 1989-03-29 EP disclosed
EP-0192148-B1 2,4-DICHLOROTHIAZOLE DERIVATIVES AND PROCESS FOR THEIR PREPARATION BAYER AG (DE) 1989-01-18 EP disclosed
US-4788291-A SELECTIVE BAYER AKTIENGESELLSCHAFT (DE) 1988-11-29 US disclosed
US-4788208-A FUNGICIDES; INTERMEDIATES FOR HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 1988-11-29 US disclosed
EP-0195237-B1 4,5-SUBSTITUTED-1,3-THIAZOL-2-YLOXYACETAMIDE BAYER AG (DE) 1988-11-02 EP disclosed
EP-0195237-A1 4,5-Substituted-1,3-thiazol-2-yloxyacetamide BAYER AG (DE) 1986-09-24 EP disclosed
EP-0192148-A1 2,4-Dichlorothiazole derivatives and process for their preparation BAYER AG (DE) 1986-08-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11369113-B2 Vector control compositions, methods and products utilizing same DDT, MSMO1, MGLL CYP3A4 139/4885TSHR 4883/4885
US-20200315175-A1 Vector Control Compositions, Methods And Products Utilizing Same DDT, MSMO1, MGLL CYP3A4 139/4885TSHR 4883/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.