Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA7 | P43166 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9504654 | 1.00 | CA1 (0.46) | CA1CA2CA7CA9KMT2A | |
| SCHEMBL23720452 | 0.86 | TSHR (0.44) | CA1CA2CA7CA9KMT2A | |
| SCHEMBL7420005 | 0.84 | TRPA1 (0.52) | CA1CA2CA7CA9KMT2A | |
| SCHEMBL12636372 | 0.84 | KMT2A (0.50) | CA1CA2CA7CA9KMT2A | |
| SCHEMBL17170433 | 0.83 | TRPA1 (0.45) | CA1CA2CA7CA9KMT2A | |
| SCHEMBL22571978 | 0.81 | CA1 (0.54) | CA1CA2CA7CA9KMT2A | |
| SCHEMBL5981451 | 0.81 | KMT2A (0.44) | CA1CA2CA7CA9KMT2A | |
| SCHEMBL14372163 | 0.81 | CA1 (0.47) | CA1CA2CA7CA9KMT2A | |
| SCHEMBL9838648 | 0.81 | CA1 (0.47) | CA1CA2CA7CA9KMT2A | |
| SCHEMBL19390430 | 0.81 | CA1 (0.47) | CA1CA2CA7CA9KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0546115-A1 | PEPTIDES CONTAINING AMINO-POLYOLS AS TRANSITION-STATE MIMICS | THE UPJOHN COMPANY (US) | 1993-06-16 | — | — | EP | disclosed |