SCHEMBL9504652

SCHEMBL9504652

[CH2]CCCCC(=O)N(CCC)N(C)C

nearest known ligand 0.42

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.42
KDM5A P29375 12/20 0.40
KDM4C Q9H3R0 11/20 0.40
KDM5C P41229 1/20 0.37
KDM5B Q9UGL1 1/20 0.37
PHF8 Q9UPP1 2/20 0.36
KDM4A O75164 2/20 0.36
LMNA P02545 1/20 0.34
EPHX2 P34913 2/20 0.34
HPGD P15428 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9507720 0.94 ALDH1A1 (0.43) ALDH1A1KDM5AKDM4CKDM5CKDM5B
SCHEMBL9504634 0.85 ALDH1A1 (0.47) ALDH1A1KDM5AKDM4CKDM5CKDM5B
SCHEMBL3292305 0.84 ALDH1A1 (0.50) ALDH1A1KDM5AKDM4CPHF8EPHX2
SCHEMBL2454690 0.84 ALDH1A1 (0.50) ALDH1A1KDM5AKDM4CPHF8EPHX2
SCHEMBL2456376 0.84 ALDH1A1 (0.50) ALDH1A1KDM5AKDM4CPHF8EPHX2
SCHEMBL28504227 0.84 ALDH1A1 (0.50) ALDH1A1KDM5AKDM4CPHF8EPHX2
SCHEMBL1568378 0.84 ALDH1A1 (0.50) ALDH1A1KDM5AKDM4CPHF8EPHX2
SCHEMBL2460311 0.84 ALDH1A1 (0.50) ALDH1A1KDM5AKDM4CPHF8EPHX2
SCHEMBL7552637 0.81 EPHX2 (0.47) ALDH1A1KDM5AKDM4CKDM5CKDM5B
SCHEMBL7555480 0.81 EPHX2 (0.47) ALDH1A1KDM5AKDM4CKDM5CKDM5B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0434354-B1 SEPARATION MATERIAL FOR BLOOD COAGULATION FACTOR, PREPARATION AND USE THEREOF KURITA WATER INDUSTRIES LTD. (JP) 1993-08-11 EP disclosed
EP-0434354-A1 Separation material for blood coagulation factor, preparation and use thereof KURITA WATER INDUSTRIES LTD. (JP) 1991-06-26 EP disclosed