Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5276371 | 0.75 | ALDH1A1 (0.44) | ALDH1A1TP53MAPK1HPGD | |
| SCHEMBL4196105 | 0.69 | — | — | |
| SCHEMBL7875334 | 0.69 | — | — | |
| SCHEMBL687481 | 0.67 | — | — | |
| SCHEMBL422868 | 0.67 | — | — | |
| SCHEMBL28530303 | 0.67 | EPHX1 (0.61) | ALDH1A1SMN1; SMN2EPHX2RAB9AMAPT | |
| SCHEMBL249032 | 0.66 | — | — | |
| SCHEMBL165882 | 0.65 | — | — | |
| SCHEMBL29034411 | 0.65 | — | — | |
| SCHEMBL14289080 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5223520-A | Insecticides | CIBA-GEIGY CORPORATION (US) | 1993-06-29 | — | — | US | disclosed |
| EP-0507736-A1 | Heterocyclic amidine derivatives and their use as pesticides | CIBA-GEIGY AG (CH) | 1992-10-07 | — | — | EP | disclosed |