Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.55 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.55 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.49 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 3/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.47 |
| ▸ | F7 | P08709 | 3/20 | 0.46 |
| ▸ | F3 | P13726 | 3/20 | 0.46 |
| ▸ | MMP2 | P08253 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | ECE1 | P42892 | 1/20 | 0.46 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.46 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.46 |
| ▸ | MUS81 | Q96NY9 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14672873 | 1.00 | CYSLTR2 (0.55) | CYSLTR2CYSLTR1SOAT2SOAT1FAAH | |
| SCHEMBL22439053 | 1.00 | CYSLTR2 (0.55) | CYSLTR2CYSLTR1SOAT2SOAT1FAAH | |
| SCHEMBL9504864 | 1.00 | CYSLTR2 (0.55) | CYSLTR2CYSLTR1SOAT2SOAT1FAAH | |
| SCHEMBL22439056 | 1.00 | CYSLTR2 (0.55) | CYSLTR2CYSLTR1SOAT2SOAT1FAAH | |
| SCHEMBL10496494 | 0.98 | CYSLTR2 (0.53) | CYSLTR2CYSLTR1SOAT2SOAT1FAAH | |
| SCHEMBL10496500 | 0.98 | CYSLTR2 (0.53) | CYSLTR2CYSLTR1SOAT2SOAT1FAAH | |
| SCHEMBL11213197 | 0.94 | PDE5A (0.49) | CYSLTR2CYSLTR1SOAT2SOAT1KDM4E | |
| SCHEMBL11213193 | 0.94 | PDE5A (0.49) | CYSLTR2CYSLTR1SOAT2SOAT1KDM4E | |
| SCHEMBL28684404 | 0.88 | CYSLTR2 (0.52) | CYSLTR2CYSLTR1SOAT2SOAT1FAAH | |
| SCHEMBL4089995 | 0.87 | PTPN1 (0.43) | CYSLTR2CYSLTR1KDM4EALOX15ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0161939-B1 | ARYLHYDROXAMATES | E.R. Squibb & Sons, Inc. (US) | 1993-07-21 | — | — | EP | disclosed |
| US-4607053-A | L2POXYGENASE INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1986-08-19 | — | — | US | disclosed |
| EP-0161939-A2 | Arylhydroxamates | E.R. Squibb & Sons, Inc. (US) | 1985-11-21 | — | — | EP | disclosed |