Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CXCR5 | P32302 | 2/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.41 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.41 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.41 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.41 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.41 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.41 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.41 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11213197 | 0.90 | PDE5A (0.49) | PTPN1ALDH1A1CYP2C9HPGDCYSLTR2 | |
| SCHEMBL11213193 | 0.90 | PDE5A (0.49) | PTPN1ALDH1A1CYP2C9HPGDCYSLTR2 | |
| SCHEMBL10496500 | 0.89 | CYSLTR2 (0.53) | ALDH1A1ALOX15CYP2C9HPGDCYSLTR2 | |
| SCHEMBL10496494 | 0.89 | CYSLTR2 (0.53) | ALDH1A1ALOX15CYP2C9HPGDCYSLTR2 | |
| SCHEMBL14672873 | 0.87 | CYSLTR2 (0.55) | ALDH1A1ALOX15CYSLTR2CYSLTR1KDM4E | |
| SCHEMBL22439053 | 0.87 | CYSLTR2 (0.55) | ALDH1A1ALOX15CYSLTR2CYSLTR1KDM4E | |
| SCHEMBL9504864 | 0.87 | CYSLTR2 (0.55) | ALDH1A1ALOX15CYSLTR2CYSLTR1KDM4E | |
| SCHEMBL22439056 | 0.87 | CYSLTR2 (0.55) | ALDH1A1ALOX15CYSLTR2CYSLTR1KDM4E | |
| SCHEMBL9504870 | 0.87 | CYSLTR2 (0.55) | ALDH1A1ALOX15CYSLTR2CYSLTR1KDM4E | |
| SCHEMBL966581 | 0.86 | ALDH1A1 (0.46) | PTPN1ALDH1A1ALOX15CYP2C9HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230051453-A1 | BIOSYNTHETIC PLATFORM FOR THE PRODUCTION OF OLIVETOLIC ACID AND ANALOGUES OF OLIVETOLIC ACID | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-02-16 | — | — | US | disclosed |
| EP-4087932-A1 | BIOSYNTHETIC PLATFORM FOR THE PRODUCTION OF OLIVETOLIC AVID AND ANALOGUES OF OLIVETOLIC ACID | The Regents of the University of California (US) | 2022-11-16 | — | — | EP | disclosed |
| EP-3377473-A1 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | RQX Pharmaceuticals, Inc. (US) | 2018-09-26 | — | — | EP | disclosed |
| US-20120270838-A1 | SPIROIMIDAZOLONE DERIVATIVE | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2012-10-25 | — | — | US | disclosed |
| EP-1680109-A4 | AMIDE DERIVATIVES AS ION-CHANNEL LIGANDS AND PHARMACEUTICAL COMPOSITIONS AND METHODS OF USING THE SAME | RENOVIS INC (US) | 2009-05-06 | — | — | EP | disclosed |
| US-20080312237-A1 | Amide derivatives as ion-channel ligands and pharmaceutical compositions and methods of using the same | RENOVIS, INC. | 2008-12-18 | — | — | US | disclosed |
| US-7432281-B2 | Amide derivatives as ion-channel ligands and pharmaceutical compositions and methods of using the same | RENOVIS, INC. (US) | 2008-10-07 | — | — | US | disclosed |
| EP-1680109-A1 | AMIDE DERIVATIVES AS ION-CHANNEL LIGANDS AND PHARMACEUTICAL COMPOSITIONS AND METHODS OF USING THE SAME | Renovis, Inc. (US) | 2006-07-19 | — | — | EP | disclosed |
| US-20050222200-A1 | AMIDE DERIVATIVES AS ION CHANNEL LIGANDS AND PHARMACEUTICAL COMPOSITIONS AND METHODS OF USING THE SAME | RENOVIS, INC. (US) | 2005-10-06 | — | — | US | disclosed |
| WO-2005046683-A1 | AMIDE DERIVATIVES AS ION-CHANNEL LIGANDS AND PHARMACEUTICAL COMPOSITIONS AND METHODS OF USING THE SAME | RENOVIS, INC. (US) | 2005-05-26 | — | — | WO | disclosed |
| EP-1280757-A2 | NEW GAMMA SELECTIVE RETINOIDS | F. HOFFMANN-LA ROCHE AG (CH) | 2003-02-05 | — | — | EP | disclosed |
| WO-2001083438-A2 | NEW GAMMA SELECTIVE RETINOIDS | F. HOFFMANN-LA ROCHE AG (CH) | 2001-11-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120270838-A1 | SPIROIMIDAZOLONE DERIVATIVE | WNK3, REN, SGK3 | PTPN1 970/4885ALDH1A1 836/4885ALOX15 4747/4885 |
| US-20080312237-A1 | Amide derivatives as ion-channel ligands and pharmaceutical compositions and methods of using the same | TRPV1, TRPA1, TRPV2 | PTPN1 2103/4885ALDH1A1 1821/4885ALOX15 443/4885 |
| US-20050222200-A1 | AMIDE DERIVATIVES AS ION CHANNEL LIGANDS AND PHARMACEUTICAL COMPOSITIONS AND METHODS OF USING THE SAME | TRPV1, TRPA1, TRPV2 | PTPN1 1578/4885ALDH1A1 1496/4885ALOX15 526/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.