Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | MIF | P14174 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8420527 | 0.88 | TDP1 (0.48) | LMNATDP1CYP1A2KMT2APOLB | |
| SCHEMBL28466560 | 0.87 | CYP1A2 (0.51) | LMNATDP1CYP1A2KMT2APOLB | |
| SCHEMBL29176913 | 0.86 | CYP1A2 (0.50) | LMNATDP1CYP1A2KMT2APOLB | |
| SCHEMBL8228438 | 0.83 | MIF (0.52) | LMNATDP1CYP1A2PPARGGSK3B | |
| SCHEMBL29176923 | 0.82 | SMN1; SMN2 (0.42) | LMNAKMT2ASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL29176926 | 0.82 | SMN1; SMN2 (0.42) | LMNAKMT2ASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL8196049 | 0.80 | TAS1R3 (0.50) | LMNATDP1CYP1A2KMT2APOLB | |
| SCHEMBL8196051 | 0.80 | TAS1R3 (0.50) | LMNATDP1CYP1A2KMT2APOLB | |
| SCHEMBL28453512 | 0.77 | MIF (0.48) | LMNACYP1A2POLBSMN1; SMN2L3MBTL1 | |
| SCHEMBL13925574 | 0.76 | MIF (0.66) | CYP1A2KMT2ASMN1; SMN2L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0373549-B1 | AMINO ACID DERIVATIVES WITH ENZYME-INHIBITING PROPERTIES, PROCESS TO SYNTHETISE THEM, COMPOSITION CONTAINING THEM AND THEIR USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-09-01 | — | — | EP | disclosed |
| US-5185324-A | ENZYME-INHIBITING AMINO ACID DERIVATIVES, A PROCESS FOR THE PREPARATION THEREOF, AGENTS CONTAINING THESE, AND THE USE THEREOF | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-02-09 | — | — | US | disclosed |
| EP-0373549-A2 | Amino acid derivatives with enzyme-inhibiting properties, process to synthetise them, composition containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-06-20 | — | — | EP | disclosed |