Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 15/20 | 0.81 |
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.80 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9501979 | 0.89 | DHODH (1.00) | DHODHPDE10ALMNATSHRCYP2D6 | |
| Oxycinchophen SCHEMBL29460357 | 0.89 | DHODH (1.00) | DHODHPDE10ALMNATSHRCYP2D6 | |
| Oxycinchophen SCHEMBL31654029 | 0.89 | DHODH (1.00) | DHODHPDE10ALMNATSHRCYP2D6 | |
| Oxycinchophen SCHEMBL1170683 | 0.89 | DHODH (1.00) | DHODHPDE10ALMNATSHRCYP2D6 | |
| SCHEMBL9501990 | 0.87 | DHODH (0.84) | DHODHPDE10A | |
| SCHEMBL9503660 | 0.86 | DHODH (0.78) | DHODHPDE10A | |
| SCHEMBL9501955 | 0.85 | DHODH (0.81) | DHODHPDE10ALMNACYP2D6CYP2C19 | |
| SCHEMBL18075840 | 0.85 | DHODH (0.78) | DHODHPDE10A | |
| SCHEMBL9502018 | 0.85 | DHODH (0.81) | DHODHPDE10ALMNATSHRCYP2D6 | |
| SCHEMBL10581516 | 0.83 | DHODH (0.76) | DHODHPDE10ALMNATSHRCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0305952-B1 | SUBSTITUTED 2-PHENYL-4-QUINOLINE-CARBOXYLIC ACIDS | AMERICAN CYANAMID COMPANY (US) | 1993-06-02 | — | — | EP | disclosed |
| EP-0305952-A1 | Substituted 2-phenyl-4-quinoline-carboxylic acids | AMERICAN CYANAMID COMPANY (US) | 1989-03-08 | — | — | EP | disclosed |